background: postoperative pain control after cesarean section (c/s) is important because inadequate postoperative pain control can result in a prolonged hospital stay. in this study, we compared postoperative somatic wound pain control between patients receiving tramadol and bupivacaine, infiltrated at the wound site. methods: in this randomized clinical trial, 98 patients, eligible for electiv...

OBJECTIVE To evaluate the effects of therapeutic hypothermia (HT) of 33 degrees C after cardiac arrest (CA) on cardiac arrhythmias, heart rate variability (HRV), and their prognostic value. DESIGN Prospective, comparative substudy of a randomized controlled trial of mild HT after out-of-hospital CA, the European Hypothermia After Cardiac Arrest study. SETTING Intensive care unit of a tertia...

the aim of this randomized clinical study was to investigate the effectiveness of acetaminophen 650 mg or liquefied ibuprofen 400 mg in pain control of orthodontic patients during separation with an elastic separator. a total of 101 patients with specific inclusion criteria were divided randomly into three groups (acetaminophen, liquefied ibuprofen, and placebo). they were instructed to take th...

To determine the optimal time of folinic acid rescue after methotrexate (MTX) treatment in patients with ALL, we selected and evaluated relevant studies that included doses, rescue delay, and side effects. Rescue at 42-48 hours resulted in considerable toxicity, except when low doses of MTX were used (1 g/m(2)) or serum MTX levels remained consistently low at 24, 30, and 36 hours. Rescue starte...

Heavy metal impregnation of specimens for electron microscopy offers a means for differential "staining" of various tissue components and cellular constituents. Of many silver impregnation methods, one of the most useful is Gomori's silver methenamine (1) after periodic acid oxidation (PA-SM) (2, 3). Several authors have applied silver impregnation to electron microscopy (4-7), mainly for the d...

AIM To compare T-tube and pressure support ventilation (PSV) as two methods of mechanical ventilation weaning of patients with chronic obstructive pulmonary disease (COPD) after failed extubation. METHODS A prospective randomized trial carried out at the multidisciplinary intensive care unit (ICU) over 2 years included 136 patients with COPD who required mechanical ventilation longer than 24 ...

BACKGROUND About 90 % of patients with intra-thoracic malignancy experience breathlessness. Breathing training is helpful, but it is unknown whether repeated sessions are needed. The present study aims to test whether three sessions are better than one for breathlessness in this population. METHODS This is a multi-centre randomised controlled non-blinded parallel arm trial. Participants were ...