Vitamin E is an established antioxidant. However, the effect of vitamin on healthspan, which deteriorates during ageing, has not been determined because most related studies have emphasized its effects lifespan. Therefore, purpose this study was to determine palm tocotrienol-rich fraction (TRF) lifespan, locomotion and thermotolerance Caenorhabditis elegans, share many common gene sequences wit...

Terminal Restriction Fragment (TRF) patterns, also known as Terminal Restriction Fragment Length Polymorphisms (T-RFLP), are a recently introduced PCR-based tool for studying microbial community structure and dynamics. Since the first review of TRF methodology (Marsh, 1999. Curr. Op. Microbiol. 2: 323-7), at least 35 new research articles were published that include this powerful tool in some p...

Tocotrienols, isomers of vitamin E, have been found to possess many health benefits. The present study was designed to determine whether tocotrienol has a direct cardioprotective role. Isolated rat hearts were perfused for 15 min with Krebs-Ringer bicarbonate buffer in the absence or presence of palm tocotrienol derived from the tocotrienol-rich fraction (0.035%) of palm oil (TRF). In another g...

Genomic DNA sequence is very abundant in periodic patterns, which play important biological roles, such as gene expression, genome structural stabilization, and recombination. Tandem repeat is a type of periodic patterns and concerns several genetic diseases. Tandem repeat finder (TRF) [1] is one of the widely used programs to find tandem repeats without a priori knowledge. Statistical models a...

TRF(Thyrotrophin-Releasing-Factor) is produced in the anterior hypothalamus, deposited in the neurohypophysis, and then passed into the cerebrospinal fluid and the blood stream to be excreted into urine(Shibusawa et al., 1959c). It has been demonstrated neither in the median and posterior hypothalamus, nor in other tissues, and body fluids. It is an hitherto unknown hormone which controls the t...

Abstract Background tRNA-derived fragments (tRFs) are 14–40-nucleotide-long, small non-coding RNAs derived from specific tRNA cleavage events with key regulatory functions in many biological processes. Many studies have shown that tRFs associated Argonaute (AGO) complexes and inhibit gene expression the same manner as miRNAs. However, there currently no tools for accurately predicting tRF targe...

BACKGROUND Vitamin E supplements containing tocotrienols are now being recommended for optimum health but its effects are scarcely known. The objective was to determine the effects of Tocotrienol Rich Fraction (TRF) supplementation on lipid profile and oxidative status in healthy older individuals at a dose of 160 mg/day for 6 months. METHODS Sixty-two subjects were recruited from two age gro...

A randomized controlled trial was conducted to examine eight weeks of resistance training (RT) with and without time-restricted feeding (TRF) in order to assess nutrient intake and changes in body composition and muscular strength in young recreationally active males. The TRF programme consisted of consuming all calories within a four-hour period of time for four days per week, but included no ...

Withdrawn behavior (WB) relates to many developmental outcomes, including pervasive developmental disorders, anxiety, depression, psychosis, personality disorders and suicide. No study has compared the latent profiles of different informants' reports on WB. This study uses multi-informant latent class analyses (LCA) of the child behavior checklist (CBCL), teacher report form (TRF) and youth sel...

There is evidence that telomeres, the ends of chromosomes, serve as clocks that pace cellular aging in vitro and in vivo. In industrialized nations, pulse pressure rises with age, and it might serve as a phenotype of biological aging of the vasculature. We therefore conducted a twin study to investigate the relation between telomere length in white blood cells and pulse pressure while simultane...