Are one-time pads a thing of the past? There has been quite a bit discussion and some security and cryptography experts argue that one-time pad is no longer a system for today's needs, that it is impractical and creates enormous key distribution problems. They say that current computer algorithms provide enough security and public key schemes solve the problem of key distribution. That's all tr...

We have investigated effects of excluded volume interactions on the translational diffusion of hydrodynamically anisotropic molecules. For that, we have performed rigid-body Brownian dynamics simulations of aqueous solutions of hen egg-white lysozyme (HEWL), at concentrations ranging from 1.25 mg/mL to 250 mg/mL and evaluated the lysozyme's self-diffusion. In the long time limit (above 1 μs), t...

Background: The expression of bio-therapeutic proteins in mammalian cells, such as CHO, attains high homogeneity related to post-translational modifications. Although CHO remains the most popular cell line for bestselling biotherapeutic proteins on the market, there are still drawbacks such as expensive culture media, long time line, and high drug cost. Recently, researches on a novel Leishmani...

In this paper, vibration analysis of multiple-stepped Bernoulli-Euler and Timoshenko beams carrying point masses is presented analytically for various boundary conditions. Each attached element is considered to have both translational and rotational inertias. The method of solution is “transfer matrix method” which is based on the changes in the vibration modes at the vicinity of any discontinu...

setback in elevation of a structure is a special irregularity with considerable effect on its seismic performance. this paper addresses multistory reinforced concrete (rc) frame buildings, regular and irregular in elevation. several multistory reinforced concrete moment resisting frames (rcmrfs) with different types of setbacks, as well as the regular frames in elevation, are designed according...

verifying the behavior of shear walls in a tall building requires reliable response results. this paper examined nonlinear fiber element modeling of a slender reinforced concrete shear wall during large-scale shaking table testing. the goal was to understand and validate the inelastic responses given by fiber models using time history analysis. reasonable agreement was found between the numeric...