Metallo-β-lactamases (MβL) catalyzing the hydrolytic cleavage of the four-membered β-lactam ring in broad spectrum of antibiotics and therefore inactivating the drug; However, the mechanism of these enzymes is still not well understood. Electronic structure and electronic energy of metallo-β-lactamase active center, two inhibitors of this enzyme including penicillin and cephalexin, and differen...

showing the occurrence of glass/rubber transition in bovine serum albumin (a globular protein) atlow moisture levels and the occurrence of maillard crosslinking in gelatin in previous works, the importanceof the state of glass or rubber of bsa on the rate and extent of polymerisation, protein solubility, colour andsds page patterns in the presence and absence of ascorbic acid, diketogulonic aci...

We investigate the storage of light in an atomic sample with a Lambda-type coupling scheme driven by optical fields at variable two-photon detuning. In the presence of electromagnetically induced transparency (EIT), light is stored and retrieved from the sample by dynamically varying the group velocity. It is found that for any two-photon detuning of the input light pulse within the EIT transpa...

We extract transition amplitudes among matter constituents of the universe from the solutions of the Wheeler De Witt equation. The physical interpretation of these solutions is then reached by an analysis of the properties of the transition amplitudes. The interpretation so obtained is based on the current carried by these solutions and confirms ideas put forward by Vilenkin.

Ab initio calculations at HF/6-31G* level of theory for geometry optimization and MP2/6-31G*//HF/6-31G* for a single point total energy calculation are reported for the importantenergy-minimum conformations and transition-state geometries of 1, 3-diazacyclohepta-1, 2-diene (2) and 1, 3-diazacycloocta-1, 2-diene (3). The C2 symmetric twist-chair (2-TC)conformation of 2 is calculated to be 7.4 kJ...