Subcutaneous fat necrosis of the newborn is an uncommon disorder occurring during the prenatal stage. Generally occurring in full-term neonates or during the first four weeks after a traumatic delivery, the disorder is characterized by the appearance of hard subcutaneous nodules or plaques on the trunk, buttocks or thighs. It is normally a benign and transient condition, although it may be comp...

The stimulation of parathyroid hormone (PTH) secretion by hypocalcemia is reduced when hypocalcemia is preceded by hypercalcemia. The present study investigates whether the duration and degree of hypercalcemia influence the reduced PTH response to hypocalcemia after hypercalcemia. In addition, the implication of the arachidonic acid (AA) signaling pathway in this effect is evaluated. The PTH re...

BACKGROUND The most common complication which occurs after thyroidectomy is postoperative hypocalcemia due to parathyroid gland damage. It usually appears 24-48 hours postoperatively, but there are clinical and biochemical factors which may contribute to its earlier diagnosis. OBJECTIVES The aim of this study was to assess clinical and biochemical factors which can influence postoperative hyp...

OBJECTIVE To investigate the influence of acute and chronic hypercalcemia on the parathyroid hormone (PTH) response to hypocalcemia. DESIGN The PTH response to hypocalcemia has been evaluated in three groups of rabbits: Group I, normal rabbits, Group II, normal rabbits subjected to an acute hypercalcemic clamp (induced by CaCl(2) infusion) and Group III, rabbits with chronic hypercalcemia (du...

In the present study the Authors tried and assess the advantages of the standard sutureless thyroidectomy performed by the Ligasure Vessel Sealing System, thanks to the use of the dedicated Precise handle. The Authors compared the efficacy of haemostasis and the economical impact of the device, in terms of drug administration and costs. The Authors comparatively analyzed 120 total extracapsular...

Hypercalcemia is a rare complication of malignancy in children. We present two children, one of whom is the youngest reported, with CALLA+ B-cell acute lymphoblastic leukemia (ALL) who developed hypercalcemia at the time of diagnosis and were treated with relatively low-dose (0.5 mg/kg) intravenous pamidronate successive to conventional therapy. No major side effects were encountered except tra...

Result: A 43-year-old man with a history of diabetes mellitus presented with vomiting, diarrhea and fatigue for 2 days and his laboratory tests showed high serum glucose and diabetic ketoacidosis. CT scan of the abdomen showed no abnormity. Intravenous fluid resuscitation and continuous insulin infusion was initiated. Omeprazole was started for possible upper gastrointestinal hemorrhage. Hypoca...

Objective: Primary hyperparathyroidism is a common endocrine disease with autonomic production of parathormone from one or more the parathyroid glands. PTx recommended for patients who meet criteria surgical treatment in guidelines. The purpose present study was to evaluate clinical and biomarker characteristics PHPT underwent light policies. Material Methods: conducted 152 that were followed o...

Hypocalcemia is a curable cause of myocardial dysfunction and clinical congestive cardiac failure, with only stray reports available in literature. We describe 15 infants presenting with severe left ventricular dysfunction, who were found to have hypocalcemia with or without hypomagnesemia. Vitamin D deficiency was identified as the main cause of hypocalcemia. These children improved on supplem...

Considering the fact that early hypocalcemia is the most common type of neonatal hypocalcemia which manifests during the first few days of Iife (72 hours) and that hypocalcemia in low birth weight neonates is very common, this descriptive study on hypocalcemia was conducted to determine the frequency of hypocalcemia in low birth weight neonates in the city of Kashan in the first 9 months of...