نتایج جستجو برای: transdermal system

تعداد نتایج: 2235577  

2011
Yosra SR Elnaggar Magda A El-Massik Ossama Y Abdallah

Although sildenafil citrate (SC) is used extensively for erectile dysfunction, oral delivery of SC encounters many obstacles. Furthermore, the physicochemical characteristics of this amphoteric drug are challenging for delivery system formulation and transdermal permeation. This article concerns the assessment of the potential of nanomedicine for improving SC delivery and transdermal permeation...

Journal: :International Journal of Nanomedicine 2008
Tak S Ching Patricia Connolly

This study investigated the possibility of simultaneously extracting glucose and lactate from human subjects, at the same skin location, using transdermal reverse iontophoresis. Transdermal monitoring using iontophoresis is made possible by the skin's permeability to small molecules and the nanoporous and microporous nature of the structure of skin. The study was intended to provide information...

2011
HETAL K PATEL VISHNU A PATEL

The purpose of this research was to develop a matrix-type transdermal therapeutic system containing drug Diclofenac acid, Pressure Sensitive Adhesive (PSA) like acrylic adhesive by the solvent evaporation technique. Different concentrations of Labrasol, oleic acid and triacetin were used to enhance the transdermal permeation of diclofenac acid. Polyethylene monolayer film as a backing membrane ...

Journal: :Journal of Drug Delivery and Therapeutics 2018

Journal: :iranian journal of pharmaceutical sciences 0
pavani sriram 2-2-28/3,bus stand road mahabubabad madusudhan rao yamsani director, vaagdevi group of pharmacy colleges, warangal yamsani shravan kumar department of pharmaceutics, vaagdevi college of pharmacy, india

the aim of the present study was to develop and investigate the feasibility of delivering nebivolol as a transdermal patch by iontophoresis. the passive and electrically assisted transdermal delivery of nebivolol hydrochloride by iontophoresis will improve the therapeutic efficacy and overcome the difficulties raised in oral drug delivery. because of its extensive hepatic metabolism and low dos...

Journal: :Journal of Nanomedicine & Nanotechnology 2014

Journal: :Journal of Neurogastroenterology and Motility 2016

Journal: :Journal of Pharmaceutical Negative Results 2022

Due to its reduced invasiveness, low rejection rate, and remarkable ease of administration, transdermal drug delivery (TDD) has recently become a viable alternative oral injectable administration. The medication method is treatment strategy that extraordinarily safe well-tolerated enormous potential for delivering active ingredients against variety illnesses. However, because the skin permeabil...

Ali Mohammad Tamaddon Fakhr Sadat Farvadi Hamidreza Moghimi Saeed Daneshamuz Samira Sadat Abolmaali

      Topical and transdermal drug delivery systems are noninvasive and can be self-administered with the minimization of side-effects, have received increased attention during the past few years. Nanoemulsions, emulsions sized between 20-200 nm with narrow distributions, offer several advantages for topical and transdermal delivery of pharmaceutical agents including controlled droplet size, th...

2012
Kumar Ravi Manvir Singh Rajni bala Nimrata seth A. C Rana

Transdermal drug delivery system appears to be most promising delivery system due to their merits over conventional delivery systems. Recently, various strategies have been used to augment the transdermal delivery of bioactives. Mainly, they include iontophoresis, electrophoresis, sonophoresis, chemical permeation enhancers, microneedles, and vesicular system (liposomes, niosomes, elastic lipos...

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