OBJECTIVES To describe patterns of nonprescribed use of tranquilizers by students aged 10 to 18 years and assess the sociodemographic characteristics of these adolescents and their use of other substances. METHODS A randomized and stratified sample of 47,979 students from state and private schools of the 27 Brazilian state capitals completed a self-report questionnaire. Poisson regression was...

I Woodruff, who later published with Andermotransplantation. son (20, 21) detailed observations of the I effect of these agents used alone or in cornI bination with thoracic duct drainage. SubCanine experiments. One hundred and sequent valuable studies have been con&my-four mongrel dogs weighing 10 to 25 tributed by Waksman, Gray (2), Monaco kilograms were immunized against hepatitis (9, 10) an...

Abstract The use of midazolam as a tranquilizer for anesthesia in mustelids in conjunction with the cyclohexamine ketamine is not well documented. Because midazolam is fast acting, inexpensive, and quickly metabolized, it may serve as a good alternative to other more commonly used tranquilizers. We trapped and anesthetized 27 Pacific martens (Martes caurina) in Lassen National Forest (northern ...

BACKGROUND: Prescription drug misuse among young adults is increasingly viewed as a public health concern, yet most research has focused on student populations and excluded high-risk groups. Furthermore, research on populations who report recent prescription drug misuse is limited. This study examined patterns of prescription drug misuse among high-risk young adults in Los Angeles (LA) and New ...

The changes induced by biologically active substances in the permeability to K+ and calcein of liposomes composed of egg phosphatidylcholine and cholesterol were measured simultaneously in order to rapidly screen the sizes of pores formed in a membrane, using different sized markers. The substances examined in the present study were classified into three types based on differences in the rates ...

background and objectives: many nepeta species have been commonly used in iranian folk medicine as tranquilizer, relaxant, carminative and restorative tonic for nervous and respiratory disorders. inflammation is a problem in many diseases and has an important role in brain function that can cause neurodegenerative disorders. inflamed glial cells can exacerbate neurodegenerative diseases by prod...

Perphenazine enanthate has been used in wild animals as a tranquilizer during the period of adaptation to new environments to reduce stress, mortalities and injuries. A gas chromatographic procedure for the quantitative measurement of perphenazine in otter urine has been developed and validated. The method involved an enzymatic hydrolysis with beta-glucuronidase-arylsulfatase from Helix pomatia...

Background. Prescription opioids are the most frequently misused class of prescription drug among young adults aged 18-25, yet trajectories of opioid misuse and escalation are understudied. We sought to model opioid misuse patterns and relationships between opioid misuse, sociodemographic factors, and other substance uses. Methods. Participants were 575 young adults age 16-25 who had misused op...

population. Current pharmacological approaches focus primarily on the g-aminobutyric acid (GABA)-ergic system, the major inhibitory neurotransmitter system of the central nervous system (CNS). Drugs that enhance synaptic GABA-ergic neurotransmission are widely utilized in the clinical setting for their sedative or hypnotic effects. Several classes of compounds—GABA, benzodiazepines, barbiturate...

OBJECTIVE Pimpinella anisum (P. anisum ) has different pharmacological properties such as anticonvulsant, analgesic, tranquilizer, antidepressant and anti-anxiety effects. In this study the antidepressant-like effect of aqueous and ethanolic extracts of P. anisum fruit in mice was investigated. MATERIALS AND METHODS Forced swimming test (FST) and tail suspension test (TST) were used to determ...