Background and Aims: Bilirubin has been considered an antioxidant that protects against atherosclerosis. The aim of this study was to evaluate the relationship of serum bilirubin level with the severity and complexity of coronary artery disease (CAD) and long-term outcome in the patients undergoing primary percutaneous coronary intervention (PCI). Materials and Methods: This prospective coho...

BACKGROUND Patients with type 2 diabetes (T2D) are at a high risk of developing microvascular complications, such as diabetic retinopathy (DR). Previous studies have shown that low serum bilirubin concentrations in T2D patients may increase the risk of diabetic complications. Thus, the aim of the present was to investigate the association between the prevalence of DR and serum concentrations of...

A new, simple, and rapid assay for conjugated bilirubin that does not require serum-matrix standards was developed by using the enzyme bilirubin oxidase (EC 1.3.3.5). This procedure can also be modified to measure total bilirubin. Measurements from these assays were compared with results obtained with the Sigma 605 (Jendrassik-Gróf method), Sigma 550/551 (Walters-Gerarde method), and Kodak Ekta...

BACKGROUND Intermittent hepatic inflow occlusion (IHIO) is associated with acute hyperglycemia during living donor hepatectomy when the ischemia is prolonged. Bilirubin is a potent antioxidant to play an important role for maintaining insulin sensitivity and preventing hyperglycemia. Thus, we aimed to test whether serum bilirubin level is associated with prolonged IHIO-induced intraoperative hy...

BACKGROUND/AIMS Serum bilirubin exerts antioxidant and cytoprotective effects. In addition, elevated serum bilirubin levels are associated with a decreased risk of metabolic and cardiovascular diseases. However, few studies have evaluated whether serum bilirubin is associated with non-alcoholic fatty liver disease (NAFLD), which is closely associated with other metabolic diseases. The aim of th...

OBJECTIVE To investigate the relationship between serum bilirubin and carotid atherosclerosis in patients with hypertension. PATIENTS AND METHODS Carotid artery ultrasonography was performed in 198 patients (104 males, average age of 65.6+/-7.1 years) with hypertension. Serum levels of bilirubin and C-reactive proteins (CRP) were measured at the same time. RESULTS Carotid atherosclerosis wa...

Background: Neonatal jaundice is clinically presented in 60% of full-term newborns. About 8% of newborns with jaundice have urinary tract infection (UTI) without any other clinical signs in favor of UTI. In present study we evaluated clinical and paraclinical data that help to rapid and early diagnosis of UTI in apparently healthy newborns with jaundice. Methods: From February to August 2006, 5...

To evaluate the changes of ABR values in hyperbilirubinemic newborns, 85 cases with severe jaundice (total bilirubin levels over 16 mg/dL and direct bilirubin less than 2 mg/dL) were selected from those admitted to Children's Medical Center by simple sampling method. These infants had no other problem except jaundice. ABR was taken before treatment in all cases and in some (10 cases) after...

BACKGROUND The relationships among serum bilirubin concentration, kidney function and proteinuria have yet to be fully elucidated, nor have these relationships been investigated in Korean adults. METHOD We retrospectively reviewed the medical records of Korean adults who were evaluated at Kosin University Gospel Hospital (Busan, Republic of Korea) during a five-year period from January 2005 t...

1. An 18-year-old male college freshman is referred to a gastroenterologist for evaluation of painless jaundice. He initially presented to a campus health center for evaluation of a flu-like illness with high fevers, where mild scleral icterus was noted. Initial laboratory studies revealed a normal complete blood count, normal alkaline phosphatase level, and normal alanine aminotransferase (ALT...