In pigs the extensive threonine utilization by the splanchnic tissues explains the relative inefficiency of dietary threonine conversion for body protein accretion. Two experiments were conducted to estimate the contribution of the portal drained viscera (PDV) and the liver to threonine metabolism and especially catabolism in growing pigs. In the first experiment, four pigs were surgically prep...

background liver transplantation is a life-saving intervention for many patients with end-stage liver disease. in the past, evaluation of successful liver transplantation was based on patients’ survival rate. however, in recent years this evaluation has been based on patients’ quality of life. various instruments have been developed to evaluate patients’ quality of life. nonetheless, scholars s...

in this study,oil was extracted from the liver and visceral fat of patin (pangasianodon hypophthalmus) and refined. the yield of oil after refining was 49.98%. the major yield loss (34.20%) happened during the degumming procedure. fatty acids found in the crude and refined oil were c12:0, c14:0, c14:1, c16:0, c16:1, c18:0, c18:1, c18:2, c18:3, c18:4, c20:0, c20:1, c20:4, c20:5, and c22:6. the d...

The prognosis of hepatocellular carcinoma (HCC) remains dismal. Insulin-like growth factor II (IGF-II), a fetal growth factor, is highly expressed during HCC development. We examined serum IGF-II levels and circulating IGF-II messenger RNA (mRNA) expression and analyzed the clinicopathologic characteristics in patients with liver diseases. The higher IGF-II level in the serum of patients with H...

conclusions chronic hepatitis c-related liver diseases impose a substantial economic burden on patients, families and the society. the current study provides useful information on cost of treatment and work loss for different disease states, which can be further used in cost-effectiveness evaluations. results the total annual cost per patient for chronic hepatitis c, cirrhosis and hepatocellula...

Microsomes are derived mostly from endoplasmic reticulum and are an ideal target to investigate compound metabolism, membrane-bound enzyme functions, lipid-protein interactions, and drug-drug interactions. To better understand the molecular mechanisms of the liver and its diseases, mouse liver microsomes were isolated and enriched with differential centrifugation and sucrose gradient centrifuga...

Human umbilical vein endothelial cells (HUVECs) were exposed to 100-μT, 50-Hz sinusoidal intermittent (5 min off, 10 min on) magnetic fields for 24 h. Total RNA was extracted from exposed and sham-exposed cells and was then analyzed via a DNA microarray technique. Interestingly, the expression of a subunit of the L-type Ca channel was 2.3-fold higher in exposed cells; this finding may be releva...

Background: Transient elastography (TE) is a new modality for the diagnosis of liver fibrosis caused by various etiologies. This study was conducted to determine the accuracy of TE in detecting the different stages of liver fibrosis in non-alcoholic fatty liver disease (NAFLD) patients. Methods: MEDLINE/PubMed, Embase, Ovid, Cochrane Library, American College of Physicians (ACP) Journal Club...