Statistical principles for analytical goal-setting were applied to two medical applications of drug-monitoring data: (a) individualizing dosage requirements by reference to a population-based therapeutic range or to a patient-specific decision value determined by Bayesian decision analysis, and (b) prospective dosing by using pharmaco-kinetic principles. For application a, the analytical goal f...

  Background and Objective: Laboratory errors are one of the major factors that affect the diagnosis, prognosis, treatment and monitoring in patients.The objective of study is to evaluate the frequency and type of errors in different phases of testing at the Pathology Department of the Shalamar Hospital, Lahore and to evaluate the causes of errors. Methods: This observational study was carrie...

Introduction: Emergencies are unforeseen and unpredictable situations. In these situations, people’s performance is affected by various factors that cause stress. People’s performance in such situations can also affect human error probability. The purpose of this study was to evaluate human error in emergency situations based on the fuzzy CREAM and Fuzzy Analytical Hierarchy Process (FAHP). Ma...

Cell image segmentation is a part of quantitative studies regarding cell movement and cell behavior, and it plays a critical role in molecular biology and cellular biochemistry. Therefore, it is fundamentally important to evaluate the performance levels of cell image segmentation algorithms. In our previous study, the performance metrics for cell image segmentation algorithms were proposed. The...

As with all other exposure-based M/NM compliance determinations, MSHA will address uncontrollable sampling and analytical errors (SAE) by allowing a margin of error before issuing a citation for exceeding the total carbon (TC) limit. In addition to using the sum of organic carbon (OC) and elemental carbon (EC) as a measure of total carbon (i.e. TC(OC+EC)) MSHA will employ an enforcement policy ...

OBJECTIVES Point of care testing (POCT) contributes to diagnosis and monitoring with fast testing time and easily performed assays. We evaluated the Abaxis Piccolo Xpress point of care chemistry analyzer using the Liver Panel Plus discs for our pediatric patient population at Texas Children's Hospital. DESIGN AND METHODS Analytical performance was evaluated for precision and linearity using q...

We develop a new formulation of Stein’s method to obtain computable upper bounds on the total variation distance between the geometric distribution and a distribution of interest. Our framework reduces the problem to the construction of a coupling between the original distribution and the “discrete equilibrium” distribution from renewal theory. We illustrate the approach in four nontrivial exam...

The total survey error (TSE) paradigm provides a theoretical framework for optimizing surveys by maximizing data quality within budgetary constraints. In this article, the TSE paradigm is viewed as part of a much larger design strategy that seeks to optimize surveys by maximizing total survey quality; i.e., quality more broadly defined to include user-specified dimensions of quality. Survey met...