Besides mediating primary hemostasis and thrombosis, platelets play a critical role in tissue repair and regeneration. They regulate fundamental mechanisms involved in the healing process including cellular migration, proliferation, and angiogenesis. Control of apoptosis/cell survival and interaction with progenitor cells, which are clinically relevant but poorly understood aspects of platelets...

Primary tumors can affect organ functions, either mechanically when they grow to a considerable size or via production of hormones. However, mortality of cancer patients is in most cases due to formation of secondary growths.(1) (,) (2) Consequently, various drugs are currently employed in clinical trials to impair specific steps of cancer metastasis such as mesenchymal or amoeboid cell migrati...

As the most important working area of gear, teeth play the role of transmitting load and power. Tooth line and tooth profile are the two main characteristics of the tooth surface, which affect the shape of the tooth surface, tooth meshing characteristics and contact characteristics. Taking the elliptical cylinder gear pair in the reversing device of a new type of drum pumping unit as the resear...

background and aims. hypodontia is a common developmental abnormality of dentition. this study aimed to determine tooth width in patients affected with mild hypodontia and compare the results with a control group without tooth agenesis. materials and methods. the orthodontic records of 25 patients with congenital missing of one or two teeth (hypodontia group), and 25 subjects with full dentitio...

Supporting structures derived from biological tissue have been used in numerous tissue-engineering applications. This study focuses on the immune response of human leukocytes toward decellularized or glutaraldehyde (GA) cross-linked vascular tissue in vitro. Porcine and human pulmonary roots were sterilized with antibiotics, decellularized or cross-linked with GA. Proteins of the vascular tissu...

Tooth enamel and dentine samples from 13 individuals buried in the unmarked ‘free ground’ colonial section of St Mary’s Anglican Cemetery Adelaide were analysed for oxygen strontium isotopic composition to assist with determination their geographic origin. As life history these is not well-documented historical record, data provide important information about migration mobility a South Australi...

Polycystic Kidney Disease (PKD) is a disorder that affects the kidneys and other organs, its major forms are encoded by polycystin-1 (PC1) polycystin-2 (PC2), as PKD1 PKD2. It located sandwiched inside outside cell membranes interacts with cells. This protein most active in kidney cells before birth, PC1 PC2 work together to help regulate proliferation, migration, interactions The molecular rel...

tooth discoloration induced by endodontic sealers, is a common finding that impairs aesthetic outcome of endodontic treatment. the aim of the present mini literature review, was to summarize the existing data on discoloration potential of different endodontic sealers. the research covered the article published in pubmed and google scholar from 2000 to 2015. the searched keywords included ‘tooth...