Portfolio managers claim to be able to generate abnormal returns through either superior asset selection or market timing. The Treynor and Mazuy (TM) model is the mostly used return-based approach to isolate market timing skills, but all existing corrections of the regression intercept can be manipulated by a manager who can trade derivatives. We revisit the TM model by applying the original op...

Time intervals are conventionally represented as linear segments in a one-dimensional space. An alternative representation of time intervals is the triangular model (TM), which represents time intervals as points in a two-dimensional space. In this paper, the use of TM in visualising and analysing time intervals is investigated. Not only does this model offer a compact visualisation of the dist...

The leukocyte adhesion cascade involves multiple events that efficiently localize circulating leukocytes into the injured sites to mediate inflammatory responses. From rolling to firm adhesion, the interactions between adhesion molecules have pivotal roles in increasing the avidity of leukocytes to endothelial cells. Thrombomodulin (TM), an essential anticoagulant protein in the vasculature, is...

Empirical models are important tools for relating field-measured biophysical variables to remotely sensed data. Regression analysis has been a popular empirical method of linking these two types of data to estimate variables such as biomass, percent vegetation canopy cover, and bare soil. This study was conducted in a semi-arid rangeland ecosystem of Qazvin province, Iran. This paper presents t...

Vegetation is an important part of ecosystem and estimation of fractional vegetation cover is of significant meaning to monitoring of vegetation growth in a certain region. With Landsat TM images and HJ-1B images as data source, an improved selective endmember linear spectral mixture model (SELSMM) was put forward in this research to estimate the fractional vegetation cover in Huangfuchuan wate...

The general model for retrovirus transmembrane (TM) proteins proposed by Gallaher et al. (W. R. Gallaher, J. M. Ball, R. F. Garry, M. C. Griffin, and R. C. Montelaro, AIDS Res. Hum. Retroviruses 5:431-440, 1989) suggests that all retrovirus TM proteins may contain an immunodominant domain (Imd-TM peptide) located at the apex of the TM polypeptide. Although this Imd-TM peptide has been shown to ...

This paper presents NeuTM, a framework for network Traffic Matrix (TM) prediction based on Long Short-Term Memory Recurrent Neural Networks (LSTM RNNs). TM prediction is defined as the problem of estimating future network traffic matrix from the previous and achieved network traffic data. It is widely used in network planning, resource management and network security. Long Short-Term Memory (LS...

Isothermal differential scanning calorimetry (DSC) was used to study the crystallization kinetics of amorphous lactose at 3 moisture contents. Each sample was heated to several temperatures between Tg and Tm. After subtraction of an induction time, the Avrami equation was used to model the data and a Lauritzen-Hoffman like expression used to fit the crystallization rates between Tg and Tm. The ...

Cytochrome P450 1B1 (Cyp1b1) belongs to the CYP450 superfamily of heme-binding mono-oxygenases which catalyze oxidation of various endogenous and exogenous substrates. The expression of Cyp1b1 plays an important role in the modulation of development and functions of the trabecular meshwork (TM). Mutations in Cyp1b1 have been reported in patients with primary congenital glaucoma (PCG). Mice lack...

PURPOSE MRL/MpJ mice of substrains MRL/MpJ-fas(+)/fas(+) (MRL/+) and MRL/MpJ-fas(lpr)/fas(lpr) (MRL/lpr) spontaneously develop autoimmune dacryoadenitis and sialadenitis and are a model for the human disorder Sjögren syndrome. The dacryoadenitis in both substrains appears to be Th2 in nature, with little IFN-gamma and substantial IL-4 at the site of lacrimal gland inflammation. METHODS MRL/Mp...