a 49-year-old man presented with a history of multiple sclerosis, causing him increased tone and spasticity in the lower extremities. this severely affected his ambulation and mobility. Following the titration of oral baclofen and tizanidine to maximum tolerated doses with little impact on his spasticity, the patient agreed to a trial dose of 50 μg of intrathecal baclofen (itB), which was effec...