Perchlorate, the oxidizer component in most solid rocket propellant formulations, is known to inhibit the uptake of iodide into the thyroid gland, thereby reducing production of the thyroid hormones, triiodothyronine and thyroxine (T4). Thyroid hormones regulate metabolism in endothermic organisms and are responsible for maintenance of homeothermic body temperatures. Little is known about the e...

Tuberculosis is an infectious disease that affects practically all organs, including the thyroid gland. In same time, hypofunction of gland may increase susceptibility to infection with Mycobacterium tuberculosis. Antituberculosis treatment, especially second-line drugs, can lead hypothyroidism. It has been found rifampicin, ethionamide, prothionamide and para-aminosalicylic acid are among most...

Thyroid ectopia is a dysgenesis of thyroid gland and Lingual position represents the most frequent ectopic location accounting up to 90% of ectopic cases. Hypothyroidism is commonly present because of absence of a normal thyroid gland in most instances. Primary hypothyroidism in juvenile population generally leads to retardation of linear growth and delay or even arrested puberty. We present a ...

To assess the toxicological significance of thyroidal tumor observed slightly in a long-term rat study with diniconazole, (E)-1-(2,4-dichlorophenyl)- 4,4-dimethyl-2-(1,2,4-triazol-1-yl)-1-penten-3-ol, a 3-month subacute feeding study was conducted in male Crj: CD (SD) rats by administering diniconazole in diet at concentrations of 0, 100, 1,000, or 2,000 ppm. Examinations mainly for thyroid fun...

BACKGROUND Thyroid dysfunction can induce developmental delay and failure to thrive in infancy. Congenital hypothyroidism is one of the common causes of these symptoms in infancy. By contrast, hyperthyroidism is a rare cause of these symptoms in infancy. CASE PRESENTATION A 7-month-old Japanese baby boy was examined for developmental delay and failure to thrive. Blood tests were performed, wh...

the use of panoramic radiography, due to its numerous advantages, is increasing. radiographic films used in this technique are of double emulsion (de) type which are used with intensifying screens. single emulsion (se) films can also be used. the purpose of this study was to determine the exposure parameters to achieve an appropriate optical density in these two types of films, and to estimate ...

Ectopy of the thyroid gland is an abnormal embryological development. Its occurrence in children is rare. In this study, we report the case of a 12-year-old girl that presented with dysphagia and nocturnal dyspnea. Magnetic resonance imaging confirmed the presence of a lingual thyroid. Thyroid scintigraphy showed intense and elective uptake of radiotracer at the base of the tongue. Hormonal tes...

RAISED serum levels ofprotein-bound iodine (PBI) in patients with normal thyroid function have been observed on many occasions after oral treatment with 5-chloro-7-iodo-8-hydroxyquinoline (iodochlorhydroxyquinoline, clioquinol, Enterovioform) (Thoren, 1960; Levin, Josephson & Grtnewald, 1966; Sonksen et al., 1968). It is less well appreciated that clioquinol administered topically can be absorb...

Disorders of the thyroid gland are well known in companion animals but less so in livestock. In livestock, nutritional iodine deficiencies have been of greater importance than thyroid-gland diseases, particularly in the iodine-deficient areas. Thyroid hormones have many functions in the body and, in general, regulate growth, differentiation, and the metabolism of lipids, proteins and carbohydra...