Autoimmune thyroid diseases (AITD) are characterized by the presence of thyroidspecifi c autoantibodies. These are directed against thyroid microsomes, for which the main target antigen is thyroid peroxidase (TPO), against thyroglobulin (TG), or against the thyroid stimulating hormone (TSH) receptor. AITD frequently occur in combination with other autoimmune diseases, such as myasthenia gravis,...

Background & Aims: While iodine is an essential element for the synthesis of thyroid hormones, epidemiological studies have showed that excessive iodine intake leads to autoimmune thyroid diseases, with an unknown mechanism. Previous studies have showed disturbance in the circulating cytokines could lead to autoimmune diseases. To determine the role of iodine in cytokine production and devel...

conclusions: this study provides detailed information and case samples of radiodine contamination artifacts and non-physiological, non-metastatic extra-thyroidal i-131 accumulation in whole-body i-131 imaging. introduction: radioactive iodine has been used for more than 50 years for the treatment of thyroid diseases. differentiated thyroid cancers have the ability to trap iodine. therefore, rad...

Physiological changes during gestation are important to be aware of in measurement and interpretation of thyroid function tests in women with autoimmune thyroid diseases. Thyroid autoimmune activity is decreasing in pregnancy. Measurement of serum TSH is the first-line screening variable for thyroid dysfunction also in pregnancy. However, using serum TSH for control of treatment of maternal thy...

Autoimmune thyroid diseases are common manifestations of hepatitis C infection, exacerbated by interferon-based treatment. However, the occurrence and pattern of thyroid disease in the short/medium term following the completion of IFN-based therapy is relatively unknown and there are very few previous reports regarding the specific spectrum of autoimmune thyroid disease that may follow such the...

In recent years, the authors of epidemiological studies have documented that autoimmune diseases are a major problem of modern society and are classified as diseases of civilization. Autoimmune thyroid diseases (ATDs) are caused by an abnormal immune response to autoantigens present in the thyroid gland - they often coexist with other autoimmune diseases. The most common dysfunctions of the thy...

Objective. Currently, total thyroidectomy (TT) is widely used to treat benign thyroid diseases and thyroid carcinoma. The differential diagnosis between benign and malignant thyroid disorders and the potential identification of thyroid microcarcinomas with biochemical markers remain controversial. This retrospective study aimed to estimate the prognostic validity of thyroid autoantibodies, thyr...

In recent years recombinant alpha-interferons (alpha-IFNs) have been widely used in the treatment of several hematological malignancies. Prolonged courses of IFN have been shown to induce autoantibodies and to support the exacerbation or even the development of autoimmune diseases. In this report we describe the development of symptomatic autoimmune thyroid diseases in 4 (7.4%) out of 54 patien...

BACKGROUND The wide array of available thyroid diagnostic tests can help provide accurate diagnoses for most cases of thyroid disease but can be confusing and costly when used inappropriately. METHODS Published articles were reviewed and combined with the author's clinical experience and data collected from patients. RESULTS The discussions focus on confusing aspects of thyroid diagnostic t...

A patient with dyspepsia and moderate anemia, without concomitant autoimmune diseases (in particular, thyroid pathology), is presented. An algorithm for diagnosing gastritis demon-strated.