the evolution of human blood groups, without doubt, has a history as old as man himself. there are at least three hypotheses about the emergence and mutation of human blood groups. global distribution pattern of blood groups depends on various environmental factors, such as disease, climate, altitude, humidity etc. in this survey, the collection of main blood groups abo and rh, along with some ...

The lunar geological record has much to tell us about the earliest history of the Solar System, the origin and evolution of the Earth-Moon system, the geological evolution of rocky planets, and the near-Earth cosmic environment throughout Solar System history. In addition, the lunar surface offers outstanding opportunities for research in astronomy, astrobiology, fundamental physics, life scien...

Research into Alzheimer's disease pathology and treatment has often focused on presenilin proteins. These proteins provide the key catalytic activity of the γ-secretase complex in the cleavage of amyloid-β precursor protein and resultant amyloid tangle deposition. Over the last 25 years, screening novel drugs to control this aberrant proteolytic activity has yet to identify effective treatments...

Hormones play key roles in the regulation of animal and plant life histories, particularly in the timing of transitions between prematurational stages and in the scheduling of reproduction. Furthermore, hormonal mechanisms are subject to information about the external and internal environment of the individual. Within an evolutionary radiation, the same hormone subsets often regulate the schedu...

Humans are unique, compared with our closest living relatives (chimpanzees) and early fossil hominins, in having an enlarged body size and lower limb joint surfaces in combination with a relatively gracile skeleton (i.e., lower bone mass for our body size). Some analyses have observed that in at least a few anatomical regions modern humans today appear to have relatively low trabecular density,...