INTRODUCTION Fibroblast growth factor-2 (FGF2) is an important signalling molecule contributing to angiogenesis, tumour growth and progression and its expression is implicated in breast cancer (BC) development. We investigated whether -553 T/A FGF2 gene polymorphism is associated with the risk and progression of BC in Polish women. MATERIAL AND METHODS The -553 T/A polymorphism was genotyped ...

OBJECTIVES We carried out a meta-analysis focusing on the relationship between length of AIB1 gene poly-Q repeat domain as a modifier of breast cancer (BC) susceptibility in patients with BRCA1 and BRCA2 mutation carriers. DATA SOURCES We searched MEDLINE and EMBASE for all medical literature published until February, 2012. STUDY ELIGIBILITY CRITERIA Studies were included in the meta-analys...

PURPOSE This investigation examined concurrent validity of the Children's OMNI-Resistance Exercise Scale (OMNI-RES) of perceived exertion for 10- to 14-yr-old females (N = 25) and males (N = 25) performing unilateral biceps curl (BC) and knee extension (KE) isotonic exercises. METHODS The criterion variable was total weight lifted (Wt(tot)), determined separately for females and males during ...

Poultry litter (PL) is a potentially underused fertilizer because it contains appreciable amounts of N, P, K, and micronutrients. However, treatments like composting to reduce potential pathogens, weed seeds, and odor often result in high losses of N through NH3 volatilization. Biochar (BC) has been shown to act as an absorber of NH3 and water-soluble NH4+ and might therefore reduce losses of N...

BACKGROUND The glutathione S-transferase (GST) enzyme GSTP1 utilizes byproducts of oxidative stress. We previously showed that alleles of GSTP1 that encode the Ile105-->Val105 substitution are associated with the asthma phenotypes of atopy and bronchial hyperresponsiveness (BHR). However, a further polymorphic site (Ala114-->Val114) has been identified that results in the following alleles: GST...

We apply CE for high-throughput analysis of functional markers for marker-assisted selection in rice. The accuracy, throughput and reproducibility of CE analysis for sequence-tagged site (STS) and simple sequence repeat (SSR) markers for bacterial blight resistance and aroma genes are demonstrated by using a CE system. Multiplex PCR products displayed well-differentiated allelic variants using ...

BACKGROUND C-X-C chemokine ligand 12 (CXCL12) has important implications in breast cancer (BC) pathogenesis. It is selectively expressed on B and T lymphocytes and is involved in hematopoiesis, thymocyte trafficking, stem cell motility, neovascularization, and tumorigenesis. The single nucleotide polymorphism (SNP) rs1801157 of CXCL12 gene has been found to be associated with higher risk of BC....

Downy mildew disease caused by the fungus Sclerospora graminicola Schroet, causes yield losses across the millet growing zones of Nigeria. Identification of the source of resistance and gene actions controlling resistance is useful in developing appropriate breeding strategies. Therefore there was need to study downy mildew resistance in Nigerian elite pearl millet lines. Five pearl millet pare...