Hepatitis C virus (HCV) is one of the leading causes chronic liver disease. Hepatocellular carcinoma (HCC) a major complication associated with HCV infection, significant mortality and morbidity rates. This study aimed to measure biochemical parameters RNA levels for detection severity hepatitis virus- hepatocellular carcinoma. The was conducted on 100 patients, ages ranging from 36 68 years p...

OBJECTIVE Liver dysfunction due to heart failure (HF) is known as congestive hepatopathy. It has recently been reported that liver stiffness assessed by transient elastography reflects increased central venous pressure. The Fibrosis-4 (FIB4) index (age (years) × aspartate aminotransferase (IU/L)/platelet count (109/L) × square root of alanine aminotransferase (IU/L)) is expected to be useful fo...

Liver segmentation is an important prerequisite for planning of surgical interventions like liver tumor resections. In this paper we propose a method for automated liver segmentation from images that is invariant in provisions of size, shape and intensity values. The system consists of three stages. In the first stage of the computerized system, Preprocessing of an image is done to reduce the n...

Hepatocellular carcinoma (HCC) is one of the common major malignancies worldwide and has third highest mortality rate any malignancy. The current field treatment for hepatocellular multidisciplinary in involvement a combination therapeutic approaches, among which immunotherapy modality advanced carcinoma. This review provides new ideas developing regimens improving efficacy patients with liver ...

The most serious adverse drug reaction of adalimumab (ADR) is tuberculosis reactivation. We describe a case of a 35-year-old man, with rheumatoid arthritis (RA) and hepatitis C virus genotype 1a with a liver biopsy in 2001 with a METAVIR score pattern A1 F0; he received interferon alpha 2b for six months, but treatment was suspended because of reactivation of RA. Liver function tests after trea...

Background. Hepatitis C virus (HCV) infection can exert proatherogenic activities due to its direct action on vessel walls and/or via the chronic inflammatory process involving the liver. Aims. To clarify the role of HCV in atherosclerosis development in monoinfected HCV patients at different degrees of liver fibrosis and with no risk factors for coronary artery disease. Methods. Forty-five pat...

Limited nutrient availability is a cause of intrauterine growth restriction (IUGR), a condition that has important implications for the well being of the offspring. Using the established IUGR model of maternal fasting in the rat, we investigated mechanisms that control gene expression and mRNA translation in late-gestation fetal liver. Maternal fasting for 48 h during the last one-third of gest...

Non-alcoholic fatty liver disease (NAFLD) is becoming increasingly prevalent due to the worldwide obesity epidemic and currently affects one-third of adults or about one billion people worldwide. NAFLD is predicted to affect over 50% of the world's population by the end of the next decade. It is the most common form of liver disease and is associated with increased risk for progression to a mor...

H2 receptor antagonists can rarely cause idiosyncratic drug reactions leading to acute hepatitis. Famotidine, however, is considered a relatively safe drug with regards to hepatotoxicity. We report a case of a 47 year old male with a history of hepatitis C who developed acute hepatitis on the third day of hospitalization with a dramatic rise in his liver enzymes from normal values at the time o...

Relapsing polychondritis is an immune-mediated disease associated with inflammation in cartilaginous structures and other tissues throughout the body, particularly the ears, nose, eyes, joints, and respiratory tract. Although association with other conditions is seen in about one-third of the cases, liver involvement is not usually observed in those patients. We described a case of liver involv...