In the title compound, [RhCl{P(p-FC(6)H(4))(3)}(3)]·CH(3)OH, the Rh atom adopts a distorted square-planar geometry. Rh, Cl and one P atom lie on a mirror plane, as does the solvent molecule. There are two inter-molecular hydrogen bonds, one between the methanol O atom and an aryl H atom (2.51 Å), and one between the Cl atom and the hydr-oxy H atom of methanol [2.34 (3) Å]. The complex precipita...

Two novel compounds, 2-methyl, 4-carboxy, 5-hydroxy-3,4,5,6-tetrahydropyrimidine (THP(A] and 2-methyl, 4-carboxy-3,4,5,6-tetrahydropyrimidine (THP(B] have been identified in the pool of Streptomyces parvulus by in vivo and in vitro studies. 13C and 15N were introduced into the compounds by feeding S. parvulus with 15N- and 13C-labeled L-glutamate. High resolution 13C and 15N NMR have been appli...

16 Ab",oc' In benefit-cost ani:llysis, trave l time saving represents a major determinant of the henefits from highway improvements . Current values of time arlopterl by the ~exas Highway Evaluation Mnrlel (HEEM) as we ll as those recommended by the Redbook are ~ai rly outdated. New estimates of the val ue of time for cars and trucks are needed for HEEM. Based on a telephone survey, thi s study...

The high-pressure structural behaviour of a series of binary thorium compounds ThX (X = C, N, P, As, Sb, Bi, S, Se, Te) is studied using the all-electron full potential linear muffin-tin orbital (FP-LMTO) method within the generalized gradient approximation (GGA) for the exchange and correlation potential. The calculated equlibrium lattice parameters and bulk moduli, as well as the equations of...

The concept of molecular simplification as a drug design strategy to shorten synthetic routes, while keeping or enhancing the biological activity of the lead drug, has been applied to (+)-muconin, an acetogenin with remarkable cytotoxicity. A novel approach that enables the stereoselective synthesis of such a natural compound or its enantiomer from a common precursor is described. An additional...

BACKGROUND Uses of polyherbal formulations have played a major role in traditional medicine. The present study is focused on the formulations used in traditional Thai folkloric medicine as tonics or bracers. Twenty documented polyherbal mixtures, used as nourishing tonics by the folk healers in Phatthalung and Songkhla provinces in southern Thailand, are targeted. Despite traditional health cla...

A novel bis-iodurated polyether compound, based on an unprecedented tetra-THF backbone, has been isolated as a trace by-product of the oxidation of squalene with the catalytic system RuO₂(cat.)/NaIO₄. The double erythro configuration of the central portion of the molecule furnishes the first indirect support of the previously postulated pathway operating in the oxidative pentacyclization of the...

Purpose One of the more perplexing ground water problems currently facing Bangladesh is the high concentration of arsenic in drinking water, which poses a relatively large risk to human health of this region. Traditional health practitioners (THPs) of Bangladesh primarily use medicinal plants for treatment of various ailments. The selection of any medicinal plant is a closely guarded secret and...