The hypothalamic thermoregulatory center was regarded as a black box some 20 years ago. Subsequent microelectrode exploration revealed the existence of two kinds of thermosensitive neurons in this area. Discharges of these neurons are now recorded not only from anesthetized animals but also from tissue explants, tissue slices, and unanesthetized animals as well. Neuronal responses produced by s...

Cooper, K. E. Some historical perspectives on thermoregulation. J Appl Physiol 92: 1717–1724, 2002; 10.1152/japplphysiol.01051.2001.—In this paper, selected historical aspects of thermoregulation and fever are presented as background to the application of molecular biology to thermoregulation. Temperature-sensing mechanisms, coordination of thermal information, thermoregulatory circuitry, effer...

The range of thermal control and the thermoneutral range of preterm infants under 30 weeks' gestation was calculated by extrapolation of data from studies on more mature infants. Even assuming some thermoregulatory capacity, the range of control is less than 3 degrees C, the thermoneutral range is less than 0.5 degrees C, and both are greatly influenced by the rate of transepidermal water loss....

THE MAMMALIAN BRAIN COORDINATES a range of behavioral and autonomic control mechanisms that together regulate body temperature. These mechanisms are engaged in response to temperature perturbations, which may be sensed by either cutaneous or deep body thermal sensors. Key to these thermoregulatory processes are neurons in the anterior hypothalamuspreoptic area (POA) (10). This region contains n...

Blessing and Ootsuka present in this issue of Temperature a cogent treatment of the analytical and conceptual pitfalls of 2 heavy hitters in physiology and behavior: the concept of homeostasis and the concept that most biobehavioral outcomes of a rhythmical nature are intrinsically sinusoidal and thus imbued with predictable periodicity. These conventions, the authors argue, fail to take into a...

1. In the altricial rodent, Phyllotis darwini, we found higher body temperatures and faster developmental rates of the thermoregulatory capacity in neonates born from coldthan warm-

Flexible Humidity Sensors In article number 2100103 by Kuniharu Takei and co-workers, an integrated flexible humidity temperature sensor system allows for the monitoring of physiological conditions from skin wetness temperature, under different conditions, wirelessly. The results prove possibility study a real-time continuous thermoregulatory center wearing deviceintegrated glove or attaching s...

This study aimed at determining the thermoregulatory phenotype of mice lacking transient receptor potential vanilloid-1 (TRPV1) channels. We used Trpv1 knockout (KO) mice and their genetically unaltered littermates to study diurnal variations in deep body temperature (T(b)) and thermoeffector activities under basal conditions, as well as thermoregulatory responses to severe heat and cold. Only ...