The recent increase in human lifespan, coupled with unhealthy diets and lifestyles have led to an unprecedented increase in cardiovascular diseases. Even in the presence of a wide range of therapeutic options with variable efficacy, mortality due to heart failure is still high and there is a need to identify new therapeutic targets. Genetic and in vitro studies have implicated the Notch signall...

OBJECTIVES Multiple characteristics of industrialization have been proposed to contribute to the global emergence of inflammatory bowel diseases (IBDs: Crohn disease and ulcerative colitis). Major changes in eating habits during the last decades and the effectiveness of exclusive enteral nutrition in the treatment of Crohn disease indicate the etiologic importance of dietary intake in IBDs. A u...

Chronic Inflammation is a key link between obesity and insulin resistance. We previously showed that two nutrient sensors AMP-activated protein kinase (AMPK) and SIRT1 interact to regulate macrophage inflammation. AMPK is also a molecular target of 5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside (AICAR), which has been shown to reduce insulin resistance in various animal models. Here we aim...

It is the position of the American Dietetic Association that the quality of life and nutritional status of older adults residing in health care communities can be enhanced by individualization to less-restrictive diets. The Association advocates the use of qualified registered dietitians (RDs) to assess and evaluate the need for nutrition care according to each person's individual medical condi...

We have previously shown beneficial effects of dietary protein restriction on transforming growth factor beta (TGF-beta) expression and glomerular matrix accumulation in experimental glomerulonephritis. We hypothesized that these effects result from restriction of dietary L-arginine intake. Arginine is a precursor for three pathways, the products of which are involved in tissue injury and repai...

A systematic review of the literature was conducted to review and evaluate the evidence supporting a liberalized diet for the management of diabetes mellitus in aged care homes and examine the effect of this on glycaemia, nutritional status and diabetes comorbidity risk factors. A 3 step search of eight databases followed by independent data extraction and quality assessment by two authors was ...

Intervention in food intake has been demonstrated to play an enormous role in both prevention and treatment of disease. Numerous studies indicate a clear link between cancer and diet. The substantial development of sequencing technologies has resulted in access to enormous amounts of genomics information, which resulted in the establishment of nutrigenomics as an emerging approach to link genom...

Abstract Bee's honey is one of the greatest natural gifts to humankind, and Indian Ayurveda emphasises various applications honey, viz . obesity, burns, cuts, wounds, dermatitis etc. However, all are based on their chemical composition, but they vary depending upon botanical, geographical origins, bee feed. With this background, current study aimed evaluate quality produced by stimulative diets...

Background: A patient’s level of satisfaction is considered an essential determinant for quality hospital food services, as it has been linked with nutrient intake and optimum nutritional requirements which contribute significantly to the care recovery patients. Objectives: This hospital-based cross-sectional study aims evaluate inpatient’s regarding their therapeutic diets in different wards a...