This study was performed to elucidate the relation between in vivo measurements of two-dimensional principal strains and the progression of left ventricle (LV) wall thinning during development of dilated cardiomyopathy in the protein kinase C-epsilon (PKC-epsilon) transgenic (TG) overexpressing mouse heart. Principal two-dimensional strains, E1 and E2, were determined in the LV wall of the anes...

23 To address mechanoreceptive roles of trigeminal ganglion (TG) nerve endings in the 24 inner walls of rat anterior eye chambers, we investigated the mechanotransduction 25 process and mechanosensitive (MS) channel on somata of TG neurons innervating this 26 area in vitro. Rat TG neurons innervating inner walls of anterior chambers were labeled 27 by anterior chamber injection of 1,1'-Dilinole...

The first quality assurance process for validating dose-volume histogram data involving brachytherapy procedures in radiation therapy is presented. The process is demonstrated using both low dose-rate and high dose-rate radionuclide sources. A rectangular cuboid was contoured in five commercially available brachytherapy treatment planning systems. A single radioactive source commissioned for QA...

PURPOSE To determine the effect on machine output calibration, following the TG-51 protocol, as the water temperature increasingly deviates from Standard temperature (22°C) METHODS: A water tank was set up according to TG-51 protocol. Two sets of measurements were taken and the pressure recorded. The measurements consisted of readings at different temperatures. In the first set, P(ion), P(pol),...

34 The goal of this study was to determine whether administration of the CB1-cannabinoid receptor 35 antagonist, rimonabant, would alter fatty acid flux in non-human primates. Five adult baboons (Papio 36 Sp), aged 12.1 ± 4.7y (body weight: 31.9 ± 2.1 kg) underwent repeated metabolic tests to determine fatty 37 acid and TG flux before and after 7 wks of treatment with rimonabant (15 mg/d). Anim...

BACKGROUND The old Treatment Planning Systems (TPSs) used for intracavitary brachytherapy with Cs-137 Selectron source utilize traditional dose calculation methods, considering each source as a point source. Using such methods introduces significant errors in dose estimation. As of 1995, TG-43 is used as the main dose calculation formalism in treatment TPSs. OBJECTIVES The purpose of this stu...

BACKGROUND Transgenic (TG) Ca/calmodulin-dependent protein kinase II (CaMKII)delta(C) mice have heart failure and isoproterenol (ISO)-inducible arrhythmias. We hypothesized that CaMKII contributes to arrhythmias and underlying cellular events and that inhibition of CaMKII reduces cardiac arrhythmogenesis in vitro and in vivo. METHODS AND RESULTS Under baseline conditions, isolated cardiac myo...

Dietary proteins may play a role in lipid absorption. Whether amino acids are specifically involved is unknown. We hypothesized that enterally administered L-glutamine (L-Gln) given with a lipid meal increases triglyceride (TG) absorption in rats. Mesenteric lymph fistulae and gastroduodenal feeding tubes were placed in adult male Sprague-Dawley rats. The animals received an enteral bolus of In...