OBJECTIVE The aim of this study was to carry out experiments further to our previous new formulation to modify the Leishmania major antigen that had satisfactory results previously. METHODS In this study we made a preliminary, new vaccine with the same methodology and selected two injection doses (100&200 μg/o.1 mL), three injection Groups: Leishmania plus BCG (LB), Leishmania plus new adjuva...

Teucrium polium L. (Labiatae) has long been recognized in folk medicine in the treatment of many pathophysiological implications, such as gastrointestinal disorders, inflammations, diabetes and rheumatism. In this study antimicrobial activity of two crude extracts obtained from Teucrium polium L. was tested against bacterial species. Minimum Inhibitory Concentration (MIC) and Minimum Bactericid...

Background and objectives: Amongst the serious metabolic disorders, diabetes mellitus (DM) is a common disease throughout the world. The excess of morbidity and mortality associated with DM and its complications emphasize the importance of new or alternative therapeutic strategies in prevention and treatment of this chronic disorder. Medicinal herbs grow vastly in Iran and are ...

Many species of Teucrium were used traditionally in treatment of inflammatory disorders. The present study aimed to assess the anti-inflammatory effect of methanolic extract of aerial parts of Teucrium oliverianum Ging. ex. Benth. (family, Lamiaceae). The extract was evaluated using the carrageenan-induced rat paw edema (Acute and sub-acute models), and turpentine oil–induced granuloma pouch bi...

The essential oil (EO) obtained by hydrodistillation from Teucrium polium L. was analyzed by gas chromatography and gas chromatography mass spectrometry (GC/MS). Antioxidant activity was evaluated through DPPH assay and Beta-carotene/linoleic acid assay. Twenty one components were identified representing (90.4%) of the EO. Main constituents of the essential oil were found as Spathulenol (15.06%...

abstract background:  primary dysmenorrhea is a prevalent problem and its effects decrease the quality of life in many women across the world. due to the side-effects of synthetic drugs, there is an increasing trend toward herbal medicine. the aim of this study was to research the effect of teucrium polium compared to placebo on the pain duration of dysmenorrhea.   materials and methods: this t...

possessing putative hypolipidemic effects, teucrium polium (tp) have been traditionally used as a medicinal plant in iran. the aim of the present study was to investigate this effect on the sucrose-induced insulin resistance male rat model. thirty wistar male rats weighting 180 ± 20 g were divided into five groups of six each. four groups were given sucrose 50% in drinking water for 10 weeks. i...