Testicular cancer is the most common malignancy in men 20 to 35 years of age and has an annual incidence of four per 100,000. If diagnosed early, the cure rate is nearly 99 percent. Risk factors for testicular cancer include cryptorchidism (i.e., undescended testicles), family history, infertility, tobacco use, and white race. Routine self-examination and physician screening have not been shown...

Testicular Leydig cells contain abundant cytoplasmic lipid droplets (LDs) as a cholesteryl-ester store for releasing cholesterols as the precursor substrate for testosterone biosynthesis. Here, we identified the protein composition of testicular LDs purified from adult mice by using mass spectrometry and immunodetection. Among 337 proteins identified, 144 were previously detected in LD proteome...

Undescended testicle is the most common congenital anomaly among males. Testicular tumor develops in 3-5% of the boys with a complaint of undescended testicle. The clinical presentation of malignant intra-abdominal testicular tumors ranges from asymptomatic cases to acute abdomen. In this study, we present a child with testicular tumor rupture which is observed very rarely. A 16-year-old boy pr...

An 84-year-old man presented with an enlarged scrotum. He had no gastrointestinal complaints. Scrotal ultrasonography showed a 2-cm left testicular mass and a 1-cm mass on the right. The serum PSA and -HCG were in the normal range, but his AFP level was very high. Abdominal ultrasonography revealed a huge tumor in the left lobe of liver. A bilateral orchiectomy was performed, and pathology exam...

Metastasis from urothelial carcinoma to the testis is rare. This case report presented an extremely rare case of testicular metastasis from renal pelvis carcinoma in a 69 year old man who had experienced painless left testicular swelling, after he underwent radical nephroureterectomy and bladder cuff excision for the urothelial carcinoma of left renal pelvis ten years ago. Physical examination ...

PURPOSE To evaluate the effectiveness of magnification-assisted subinguinal varicocelectomy (MASV) with testicular delivery in children with severe varicocele. MATERIALS AND METHODS We retrospectively analyzed the clinical data of 23 children 15 years or younger (mean age, 12.3±1.8 years) who underwent MASV with testicular delivery and ligation of all collateral veins except arteries and defe...

Childhood malignant testicle tumors are very rare. In the literature to date, it has been reported that there are only 24 cavernous hemangioma cases existing in English literature. In this study, we discuss a testicular mass case which was diagnosed as cavernous hemangioma. The patient, who followed for left multicystic dysplastic kidney since his birth, was admitted to our clinic with complain...

Granulomatous Orchitis secondary to lymphatic filiarisis is a rare diagnosis within the United States. We report a case of a 22yo Male from Sri Lanka, with a new onset scrotal swelling and palpable right testicular mass. Ultrasound identified a 1 cm right testicular mass with signs of tunica albuginea invasion. A right inguinal radical orchiectomy was performed and pathology showed Filarial orc...

Instrascrotal capillary haemangiomas are very rare benign tumours. They usually present as a scrotal mass, which requires scrotal exploration and tumour excision for definitive diagnosis. They can be easily misinterpreted as testicular tumours, epididymal cysts or sarcomas. Imaging is usually of limited diagnostic value, but can reliably exclude testicular cancer. Their identification is import...

Testicular epidermoid cysts are a rare cause of testicular pathology. No cases of recurrence or metastasis have been reported in the literature. As a result, inguinal partial orchiectomy with frozen section has recently become standard treatment. A 43-year-old male presented with right testicular discomfort and the presence of mass. Right inguinal partial orchiectomy with frozen section was per...