The limiting factor of the accuracy of WFPC2 photometry is the CTE loss, which has increased to the level of 50% or more for faint stars at the top of the chips. I describe recent work on characterizing this effect, and provide improved equations for CTE correction. I also examine issues affecting background measurement, which if not done correctly can introduce artificial nonlinearities into p...

The correction for the change in sensitivity with time for the STIS CCD modes is complicated by the gradual loss of charge transfer efficiency (CTE) of the CCD. The amount of this CTE loss depends on time in orbit, the location on the CCD chip with respect to the readout amplifier, the stellar signal strength, and the background level. Primary constraints on our correction algorithm are provide...

A 2022 survey showed that Americans see career preparation as a higher priority for schools than college preparation, making and technical education (CTE) increasingly relevant. Teresa Preston previews the March 2023 issue of Kappan, focused on CTE. The explores outcomes CTE programs what potential benefits might be students.

The constitutive transport element (CTE) of the simian type D retroviruses overcomes nuclear retention and allows nuclear export of unspliced viral RNAs by recruiting TAP, a host factor which is thought to be required for export of cellular mRNAs. In this report, we show that the first 372 amino acid residues of TAP, comprising a stretch of leucine-rich repeats, are both necessary and sufficien...

Hot pixels provide a potentially useful probe of CTE effects, as they can be used to measure effects at the smallest scales -at single pixel level. Herein we outline a method of using the tails on hot pixels to quantify CTE effects, and apply it to CTE tails in WFPC2 dark frames. As we show, many of the behaviors associated with photometric CTE are also found for hot pixel tails including the d...

BACKGROUND A hallmark of retroviral gene expression is that unspliced retroviral genomic RNA is exported to the cytoplasm, whereas endogenous intron-containing cellular RNAs are usually retained in the nucleus. In complex retroviruses, such as human immunodeficiency virus-1 (HIV-1), nuclear export is accomplished by the interaction of a virally encoded protein, Rev, with a cis-acting RNA elemen...

BACKGROUND Video capsule enteroscopy (VCE) has revolutionized small bowel imaging, enabling visual examination of the mucosa of the entire small bowel, while MR enteroclysis (MRE) and CT enteroclysis (CTE) have largely replaced conventional barium enteroclysis. A new indication for MRE and CTE is the clinical suspicion of small bowel strictures, as indicated by delayed or non-delivery of a test...

BACKGROUND CT enterography yields striking findings in the bowel wall in Crohn's disease. These images may help to evaluate whether small bowel narrowing results from active disease requiring anti-inflammatory therapy. However, the clinical relevance of these images is unknown. It is also not known if these radiologic findings correlate with objective biomarkers of inflammation. METHODS In a ...

Background and aims: The differential diagnosis between Crohn's disease (CD) and ischemic colitis (ISC) is important as their clinical management is different. ISC can easily be misdiagnosed as CD, especially in elderly populations. The distinctive radiographic features of the two disease entities have not been investigated. The aim of this study is to assess the utility of computed tomographic...

OPINION STATEMENT Chronic traumatic encephalopathy (CTE) is a unique neurodegenerative disease found in individuals with a history of repetitive head impacts. The neuropathology of CTE is increasingly well defined. Prospective, longitudinal studies with post-mortem neuropathologic validation as well as in vivo diagnostic techniques are needed in order to advance the understanding of CTE clinica...