BACKGROUND The Neurologic and Adaptive Capacity Score (NACS) is a multi-item scale that was published in 1982 to measure the effects of intrapartum drugs on the neonate. Although this scoring system has been widely used in obstetric anesthesia research, studies confirming its reliability have not been published. The purpose of this study was to assess the reliability of the NACS. METHODS Two ...

OBJECTIVE Adipose tissue dysfunction, characterized by dysregulation of adipokines production and/or secretion, has been implicated in the pathophysiology of type-2 diabetes mellitus, a metabolic complication closely related to gestational diabetes mellitus (GDM). Recently, an association between circulating maternal visfatin, a novel adipokine with metabolic and immunoregulatory properties, an...

3,5-dihydroxyphenylglycine (3,5-DHPG) was the first agonist shown to be group I metabotropic glutamate receptor selective with its agonist effects residing exclusively in the S-isomer. Some results suggest that (S)-3,5-DHPG may be a partial agonist of mGluR1a and mGluR5a in neurons and astrocytes. It has been reported that (S)-3,5-DHPG can, under certain conditions, interact with NMDA receptors...

Spontaneous intestinal perforation suggests a of the gastrointestinal tract no demonstrable cause. Only few such cases have been described in full term newborns. Although some authors suggested ischemia and fetal or neonatal hypoxia as most likely cause, etiology pathogenesis this disease are still widely unknown. Here, we present case neonate who was born to mother with chronic hypertension. R...

Neonatal hypoglycemia is common metabolic disorder. Hyperglycemia can also occur in other conditions like exogenous parenteral glucose administration, preterm, ELBW babies, stressed premature infants (requiring mechanical ventilation), hypoxia or neonatal diabetes mellitus. The major clinical problems associated with hyperglycemia are hyper osmolality and osmotic dieresis leading to alteration ...