In Aplysia, long-term sensitization (LTS) occurs concurrently with a suppression of feeding. At the cellular level, the suppression of feeding is accompanied by decreased excitability of decision-making neuron B51. We examined the contribution of voltage-gated Na+ and K+ channels to B51 decreased excitability. In a pharmacologically isolated Na+ channels environment, LTS training significantly ...

Long term conditions are a major challenge to the sustainability of health services globally. Their increasing prevalence is associated with growing rates of preventable complications and premature mortality, resulting in soaring costs (box 1). These factors, coupled with higher expectations among patients and the public, create an urgent need to redesign health services, which are still largel...

BACKGROUND Over half of the residents in long-term care have a diagnosis of dementia. Maintaining quality of life is important, as there is no cure for dementia. Quality of life may be used as a benchmark for caregiving, and can help to enhance respect for the person with dementia and to improve care provision. The purpose of this study was to describe quality of life as reported by people livi...

OBJECTIVE To examine the effect of changes in parent-child coresidence on caregiving decisions of non-resident siblings over a 5-year period while controlling for characteristics of the elderly parent and adult children in the family network. METHOD We use difference-in-difference models applied to Health and Retirement Study-Assets and Health Dynamics of the Elderly data to test the hypothes...

Actually using MT is not just a matter of buying a system, installing it, and feeding text through. Real-world text comes with spelling mistakes, bad grammar, missing portions, etc. But perhaps the users don't care, and just want a rough idea of what the text is about. Aspects of the environment surrounding the system and the tasks for which the output is used can contribute significantly to th...

PURPOSE The purpose of this manuscript is to discuss the need for use of evidence based practice (EBP) in LTC, the current use of evidence in long term care facilities and what we know about adoption of the use of EBP in LTC. METHODS Literature review and reporting of findings from the M-TRAIN study that was a quasi-experimental design to test the effectiveness of an intervention to increase ...

DSS was once a revolutionary idea, but in the intervening decades the original issues that led to the DSS movement have receded to ancient history. Declaring victory on the initial DSS agenda raises questions about whether DSS today is anything other than an umbrella term for disparate types of systems whose main commonality involves overlapping interests of researchers rather than substantive ...

The Real Choice Systems Change grant program was created to help states transform their long-term care service systems from ones that rely on institutions to ones that are more community-based. The grants are intended to help states develop the infrastructure needed for seniors and individuals with disabilities to live in integrated community settings. This issue brief provides information abou...

We would like to correct the last name of first author as shown below. Change is marked by underline. The authors regret this error.

OBJECTIVE To demonstrate the application of economics to health care preparedness by estimating the financial return on investment in a substate regional emergency response team and to develop a financial model aimed at sustaining community-level disaster readiness. METHODS Economic evaluation methods were applied to the experience of a regional Pennsylvania response capability. A cost-benefi...