introduction: hypothyroidism is diagnosed by elevated thyroid stimulating hormone (tsh) and normal or decreased serum levels of t4 or t3, and is associated with a wide range of m etabolic abnormalities, including anemia. this clinical study aimed to assess the improvement of anemia in patients with primary hypothyroidism following administration of levothyroxine in iranian population. materials...

abstract introduction major ß thalassemia represents a group of recessively inherited hemoglobin disorder, which is characterized by reduced synthesis of globins chains. frequent blood transfusions can lead to iron overload, which may result in several endocrine complication especially in the absence of adequate chelating therapy. the objective of this study were to determine the prevalence of ...

Less than four percent of patients with hypothyroidism develop ascites. Ascites as the presenting feature of hypothyroidism is uncommon, hence diagnosis is often delayed. Once it is diagnosed, treatment of hypothyroidism leads to quick clinical improvement in ascites. We report a case of a female patient who presented with ascites secondary to severe hypothyroidism and discuss the diagnostic ch...

Hypothyroidism is a common and well recognized cause of diffuse hair loss. Zinc and other trace elements such as copper and selenium are required for the synthesis of thyroid hormones, and deficiency of these can result in hypothyroidism. Conversely, thyroid hormones are essential for the absorption of zinc, and hence hypothyroidism can result in acquired zinc deficiency. The hair loss attribut...

purpose : vitreoretinal surgery can be difficult or impossible in patients with corneal opacity. one solution for this problem is use of temporary keratoprosthesis (tkp). we report anatomical and visual outcomes of this combined surgery in our institution. methods : we retrospectively reviewed charts of patients in whom a tkp was used between 2006 and 2010 with follow-up of at least six months....

Hypothyroidism is a common endocrine disorder resulting from deficiency of thyroid hormone or its effects on peripheral tissues. It usually is caused by an insufficient production of thyroid hormone by thyroid gland (primary hypothyroidism), but it could be also caused by inadequate secretion of either thyrotropin (ie. thyroid-stimulating hormoneTSH) from the pituitary gland (secondary hypothyr...

background: fanconi anemia (fa) is a rare, autosomal recessive (ar) and multifactorial disorder. a high prevalence of fa observed in iran is perhaps due to the high rate of consanguineous marriages. this study investigates the extent of short stature in patients with fa, the frequency of hypothyroidism in fa and the correlation between height and hypothyroidism.   methods: eighteen patients wit...

Hypothyroidism is frequently associated with different neuromuscular disorders. However, myotonia is rarely a revealing feature. We report a case of hypothyroidism secondary to Hashimoto's thyroiditis and myotonia. The patient is a 45-year-old woman who consulted for a progressive myotonia. Blood and thyroid assessments revealed peripheral hypothyroidism with low free thyroxine, high thyroid-st...

Results Thirty-four patients were included in the study. The median age at diagnosis was 7.5 years (range = 0.8 17.2 years) and the median follow-up time was 10.45 years (range = 2 – 18.3 years). Hypothyroidism was diagnosed in 16 patients (Primary hypothyroidism = 5 patients; compensated hypothyroidism = 10 patients; central hypothyroidism = 1 patients) and it was the commonest endocrine compl...

Hypothyroidism is usually associated with delayed pubertal development but in rare occasions precocious puberty may ensue which is seen in cases of prolonged and untreated hypothyroidism. This is also called the Van Wyk Grumbach syndrome. Here we present 4 cases of precocious puberty due to hypothyroidism.