BACKGROUND AND PURPOSE We describe a new rat model of temporary focal ischemia that produces neocortical ischemia without the need for prolonged anesthesia. METHODS Temporary focal cerebral ischemia was initiated during halothane anesthesia, maintained for varying periods without anesthesia, and reversed by clip removal requiring brief anesthesia. Tandem carotid and middle cerebral artery occ...

Objective: Although coronary artery disease (CAD) is the leading cause of death in type 2 diabetic patients, it is frequently asymptomatic. Myocardial perfusion imaging (MPI) is reported to show ischemia in a significant number of asymptomatic diabetic patients. We studied the prevalence and severity of myocardial perfusion defects in asymptomatic diabetic patients and its clinical impact. Meth...

Venous intestinal ischemia is a relatively rare disease, which has some predisposing factor up to 80 % of cases. These factors may be temporary or permanent. Cancer, immobilization, trauma, intraabdominal infections, or oral contraceptives are temporary factors. Paroxysmal nocturnal hemoglobinuria and hypercoagulability states as factor V Leiden, G20210A mutation in prothrombin gene, C677T meth...

Objective(s): Particulate matter (PM) exposure can promote cardiac ischemia and myocardial damage. The effects of PM10 on hemodynamic parameters, lipid peroxidation, and infarct size induced by ischemia-reperfusion injury and the protective effects of vanillic acid (VA) in isolated rat heart were investigated. Materials and Methods: Eighty male Wistar rats (250–300 g) were divided into 8 groups...

Imaging of cardiac function and anatomy has advanced at an exponential rate over the past two decades. Our ability to quantitatively assess the degree of myocardial ischemia and accurately define the vascular anatomy using noninvasive techniques is greater than ever before. Current advances is cardiac imaging are allowing us to more safely assess patients for myocardial ischemia and better unde...

bipolar cardiac electrograms were obtained in dogs from ischemic areas following temporary coronary artery ligation. characteristic alterations from the controls were observed, including increase in dura tion, decrease in amplitude and alterations in configuration. these changes were found to be completely reversible upon restoration of coronary flow. the bipolar electrogram has been recommende...