To unveil the mechanism of fast autooxidation of fish myoglobins, the effect of temperature on the structural change of tuna myoglobin was investigated. Purified myoglobin was subjected to preincubation at 5, 20, 50 and 40C. Overall helical structural decay through thermal treatment up to 95C was monitored by circular dichroism spectrometry, while the structural changes around the heme pocket w...

The purpose of this research was to determine the optimum conditions of pH, temperature and agitation rate for the biodegradation of lipids and detergent by Bacillus cereus N-09. A response surface method was used to analysis the data. The materials used in this research was the waste created by boiling instant noodles as a reference on the packaging and then diluted ten times and added a comme...

Cyclophosphamide is a widely used antitumor drug, with induced adverse effects, such as intestinal mucosal injury and immunosuppression. Norcantharidin possesses anticancer activity through enhancement of immunity. We investigated the role norcantharidin in cyclophosphamide-induced Mice were treated cyclophosphamide, exposed to norcantharidin. Enzyme-linked-immunosorbent serologic assay was per...

Size tunable Cadmium sulphide (CdS) quantum dots have been synthesized through wet chemical co-precipitation method, at three different temperatures 35C, 50C and 65C for varying pH values of 9 and 10.5 respectively. The solution was prepared using Cadmium chloride and thiourea as material precursors, ammonium hydroxide as precipitating agent and mercaptoethanol as surfactant. Thin films of thes...

Power is rapidly becoming the primary design constraint for systems ranging from server computers to handhelds. In this paper we study microarchitecture-level coupled power and thermal simulation considering dynamic and leakage power models with temperature and voltage scaling. We develop an accurate temperature-dependent leakage power model and efficient temperature calculation, and show that ...

Chebulinic acid is a phenolic compound, commonly found in the Terminalia chebula, Phyllanthus emblica, Dimocarpus longan species etc. The enhancement of Chebulinic acid was obtained from the composition of medicinal herbs by using Baker’s yeast (Saccharomyces cerevisiae) under fermentation process. The optimum results were observed for the effect of % inoculum, substrate wt, incubation period, ...

ER stress PERKs up an miRNA B yrd et al. describe how a microRNA (miRNA) fi ne-tunes a cell's response to ER stress. When stressful conditions disrupt the ER's normal function, the cell activates an unfolded protein response (UPR) that restores the organelle's ability to fold and export proteins to the secretory pathway. The transcription factor XBP1 is a key component of the UPR that boosts ER...

OBJECTIVES Whether the ultra-highly-diluted remedies used in homeopathy can effectively bring about modulations of gene expressions through acetylation/deacetylation of histones has not been explored. Therefore, in this study, we pointedly checked if the homeopathically-diluted anti-cancer remedy Condurango 30C (ethanolic extract of Gonolobus condurango diluted 10(-60) times) was capable of arr...

Author manuscripts have been peer reviewed and accepted for publication but have not yet been edited. Abstract Inactivation of the von-Hippel Lindau (VHL) tumor suppressor gene occurs in 90% of human clear cell renal cell carcinomas (ccRCC), and leads to the stable expression of the hypoxia inducible factors HIF1Į and HIF2Į. The constitutive expression of HIF1Į in a majority of VHL-deficient tu...