Introduction . Dyslipidemia treatment in many cases requires carefully selected combination of lipid-lowering drugs including bile acid sequestrants. A promising compound is L-rhamnopyranosyl-6- O -methyl-galacturonan (L-RAG), a polysaccharide obtained from the birch leaves ( Betula pendula L.). Aim To evaluate activity L-RAG administered with HMG-CoA reductase inhibitor rosuvastatin or cholest...

BACKGROUND The aim of this study was to investigate the relationship among apolipoprotein E (APOE) polymorphism, body mass index (BMI), and dyslipidemia and how these factors modify overall mortality in a cohort of hospitalized elderly patients. METHODS Plasma concentrations of total cholesterol (TC), triglycerides (TG), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein ch...

We studied the rebound of lipoproteins in 20 hypercholesterolemic men [mean total cholesterol (TC) levels 9.691.8 mmol/l] after LDL-apheresis (LA) to determine the rate of recovery and the change in cholesterol synthesis, and to find a uniform estimation for time-averaged levels. After 10–20 months on biweekly LA using dextran sulfate cellulose columns and concomitant simvastatin administration...

BACKGROUND Hypercholesterolaemia has been associated with low bone mineral density (BMD) in some but not all studies. OBJECTIVES To examine the influence of age, menopausal status and hormone replacement therapy (HRT) on the relationship between serum cholesterol and BMD in women. PATIENTS AND MEASUREMENTS 497 female participants (age range 20-81) comprising 224 premenopausal and 273 postme...

OBJECTIVE To evaluate the test performance of specific body mass index (BMI) percentile cutoffs for detecting children/adolescents with hypercholesterolemia. DESIGN Cross-sectional analysis. SETTING National Health and Nutrition Examination Survey 1999-2004. PARTICIPANTS Population-based sample of children (aged 3-18 years) with nonfasting total cholesterol (TC) and high-density lipoprote...

BACKGROUND The main purpose of this study was to evaluate the between-instrument variation of the HPLC method for the measurement of total cholesterol (TC), HDL-cholesterol (HDL-C), LDL-cholesterol (LDL-C), VLDL-cholesterol (VLDL-C), chylomicron cholesterol (CM-C), LDL size, and HDL size. Furthermore, the accuracy of the HPLC was assessed for the determination of TC and HDL-C, compared with CDC...

OBJECTIVE To investigate the role of Brachial ankle Pulse Wave Relocity (baPWV) and cfPWV on the risk of Coronary artery disease and the interaction between baPWV and risk factors of Coronary artery disease (CAD). METHODS A case-control study was conducted at Department of Emergency, SunYat-Sen memorial Hospital, China. We collected 332 cases with coronary artery disease and 328 subjects with...

Subjects with increased cholesterol absorption might benefit more from statin therapy combined with a cholesterol absorption inhibitor. We assessed whether baseline cholesterol absorption markers were associated with response to ezetimibe/simvastatin therapy, in terms of LDL-cholesterol (LDL-C) lowering and cholesterol absorption inhibition, in patients with familial hypercholesterolemia (FH). ...

The influence of type fish consumption on cardiovascular risk profiles was studied in Sri Lankan community. Achallenge experiment set up to do a research the omega-3 fatty acid content cardiovascularrisk healthy people. Hundred undergraduates (subjects) who were between ages 23 30 yearsand full time resident hostels Lanka, randomly selected for this study. students fed with fishcurry and fried ...

To identify genetic loci influencing blood lipid levels in Caribbean Hispanics, we first conducted a genome-wide linkage scan in 1,211 subjects from 100 Dominican families on five lipid quantitative traits: total cholesterol (TC), low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C), triglycerides (TG), and LDL-C/HDL-C ratio. We then investigated the associa...