Increasing production of free radicals in organisms is one of the putative mechanisms by which a extremely low frequency magnetic field (ELF-MF) may affect biological systems. The present study was designated to assess if ELF-MF applied in the magnetotherapy, affects generation of reactive oxygen species (ROS) in heart tissue and antioxidant capacity of plasma according to its working time. The...

The objective of this study was to evaluate the effect of α-ketoglutarate on redox state parameters and arterial elasticity in elderly mice. Mice in the control group were fed with standard diet, while the experimental animals received the diet supplemented either with calcium (Ca-AKG) or sodium salt of α-ketoglutarate (Na-AKG). The experimental animals were divided into 4 groups with 10 indivi...

BACKGROUND The antioxidant function of iodine and iodine deficiency as a risk factor of preeclampsia have been previously reported. AIM To analyze the association between iodine deficiency, oxidative stress and antioxidant status with hypertensive disease of pregnancy (HPD). METHOD Fifty-seven pregnant women were recruited in the last trimester of pregnancy; 20 were diagnosed with hypertens...

It has been suggested that oxidative stress is a feature of aging. The goal of the present study was to assess the oxidant effects related to aging and the protective role of exogenous melatonin in senescence-accelerated mice (SAMP8). Two groups of SAMP8 mice (males and females) were compared with their respective control groups of SAMR1 mice (senescence-resistant inbred strain) to determine th...

Although vitamin C supplements were consumed for health maintenance and fatigue recovery, the effects of high doses of vitamin C supplement remains controversial. Our study performed the effects of 100 mg and 2,000 mg vitamin C supplements on plasma and urinary vitamin C concentration in Korean women. Twenty-four women completed the 4 weeks intervention. Anthropometric data, plasma and urinary ...

Aluminium is numbered among trace elements with a moderate toxic effect on living organisms. We have attempted to assess the influence of long-term aluminium chloride intake on the biochemical parameters and oxidative stress biomarkers in experimental animals. Three months’ administration of aluminium chloride in drinking water at a dose of 80 mg/l significantly elevated blood serum urea and cr...

BACKGROUND Carissa opaca is a Pakistani fruit, traditionally used in the treatment of various human ailments including asthma and pulmonary damage. The present study investigated the protective effects of Carissa opaca against CCl4-induced oxidative stress in rat lungs. METHODS To assess the protective effects of Carissa opaca, 42 Sprague-Dawley male rats (170-180 g) were randomly divided int...

BACKGROUND The majority of studies have investigated the effect of exercise training (TR) on vascular responses in diabetic animals (DB), but none evaluated nitric oxide (NO) and advanced glycation end products (AGEs) formation associated with oxidant and antioxidant activities in femoral and coronary arteries from trained diabetic rats. Our hypothesis was that 8-week TR would alter AGEs levels...

The aim of this study was to examine the impact of Ca, Mg, Fe, Na, k, zn, Cd, and Pb upon enzymatic activity of superoxide dismutase (Sod), catalase (CAT), and ceruloplasmine (CP) diurnal and nocturnal activity, and the content of thiobarbituric acid-reactive substances (TBARS), and their interaction with free radicals, in the blood of the White Stork (Ciconia ciconia), an altricial bird, durin...

Metabolic changes during kidney and liver disease can induce increased production of oxygen radicals that play an important role in the progression damage appearance comorbidities. In study reported here, effect alpha-lipoic acid (ALA) on chemiluminescence (CL) TBARS determination microsomes isolated from rat was analyzed. Oxidative stress induced by subjecting samples (1 mg protein) to ascorba...