This work aims at investigating the impact of treating breast cancer using different radiation therapy (RT) techniques--forwardly-planned intensity-modulated, f-IMRT, inversely-planned IMRT and dynamic conformal arc (DCART) RT--and their effects on the whole-breast irradiation and in the undesirable irradiation of the surrounding healthy tissues. Two algorithms of iPlan BrainLAB treatment plann...

This retrospective analysis evaluates the treatment results and prognostic factors of 114 patients with ductal carcinoma in situ (DCIS) undergoing breast conserving therapy (BCT) at Keio University Hospital Department of Radiology, between 1988 and 1997. A total of 132 patients with DCIS of the breast came to our hospital between 1988 and 1997, and 114 cases were suitable candidates for BCT. Al...

A 71-year-old woman was referred to our unit with fever (38.5◦C). During the preceding 3 weeks she reported sweats and non-productive cough despite previous antibiotic therapy. In May 2005 she had undergone a quadrantectomy and sentinel-node biopsy at our hospital for right upperouter quadrant breast cancer. She received radiation therapy through conventional tangential-field irradiation using ...

Introduction: A high risk for development of severe side effects after radiotherapy may be correlated with high cellular radiosensitivity. To enhance radiation therapy efficiency a fast and reliable in-vitro test is desirable to identify radiosensitive patients. The aim of present study was to identify the mechanism of radiation induced DNA double-strand breaks (DSBs) and DSB r...

Background: In most cancer cases, the treatment choice for a pregnant patient is radiotherapy. In these patients, the abdomen is usually not exposed therefore fetus exposure is due to peripheral dose (PD). The purpose of this study was to estimate the fetal dose (the maximum PD in each pregnancy stage) for modalities available and to fabricate and evaluate a generally applicable fetal ...

background: radiation-induced discomfort is frequently observed during pelvic radiotherapy. this study was performed to determine the effect of a green tea tablet to reduce the incidence of radiation-induced diarrhea and vomiting in patients with abdomen and pelvic malignancy. materials and methods: this randomized controlled clinical trial recruited 42 patients with abdomen and pelvic malignan...

When we fix one side and draw different tangential quadrilaterals having the same side lengths but different angles we observe that their incenters lie on a circle. Based on a known formula expressing the incircle radius of a tangential quadrilateral by its tangent lengths, some older results will be presented in a new light and the equation of the before mentioned circle will appear. This circ...