نتایج جستجو برای: t2d

تعداد نتایج: 3280  

2011
Clara C. Elbers N. Charlotte Onland-Moret Marinus J.C. Eijkemans Cisca Wijmenga Diederick E. Grobbee Yvonne T. van der Schouw

BACKGROUND Fertility problems are frequently followed by early menopause, and early menopause has been associated with increased risk of type 2 diabetes (T2D). Thus far, it is unknown whether low fertility is independently associated with future T2D risk. METHODS We assessed the association between measures of low fertility and T2D in the Prospect-European Prospective Investigation into Cance...

2016
Sakib Jalil Rita Orji

Type 2 Diabetes (T2D) patients need constant monitoring of food, exercise and insulin level. Telemedical systems aid the patients in monitoring and sending their regular blood glucose to nurses and in receiving suggestions on food, exercise and insulin dosage, especially on food choices. This paper presents a qualitative inquiry aimed at investigating the possibility of integrating Persuasive T...

2017
Ann Oyare Amuta Rahma Mkuu Wura Jacobs Adam E. Barry

AIM A binary measurement of type 2 diabetes (T2D) has been found not to influence behaviors. We aimed to examine the influence of other measures of family history such as number of relatives, genetic closeness of relatives, and severity of T2D of family members on nutrition and physical activity behaviors among college students. METHODS Students across four colleges in Texas were sampled. Mul...

Journal: :Endocrine connections 2015
Ali Abbasi

Many biomarkers are associated with type 2 diabetes (T2D) risk in epidemiological observations. The aim of this study was to identify and summarize current evidence for causal effects of biomarkers on T2D. A systematic literature search in PubMed and EMBASE (until April 2015) was done to identify Mendelian randomization studies that examined potential causal effects of biomarkers on T2D. To rep...

Journal: :Science 2007
Laura J Scott Karen L Mohlke Lori L Bonnycastle Cristen J Willer Yun Li William L Duren Michael R Erdos Heather M Stringham Peter S Chines Anne U Jackson Ludmila Prokunina-Olsson Chia-Jen Ding Amy J Swift Narisu Narisu Tianle Hu Randall Pruim Rui Xiao Xiao-Yi Li Karen N Conneely Nancy L Riebow Andrew G Sprau Maurine Tong Peggy P White Kurt N Hetrick Michael W Barnhart Craig W Bark Janet L Goldstein Lee Watkins Fang Xiang Jouko Saramies Thomas A Buchanan Richard M Watanabe Timo T Valle Leena Kinnunen Gonçalo R Abecasis Elizabeth W Pugh Kimberly F Doheny Richard N Bergman Jaakko Tuomilehto Francis S Collins Michael Boehnke

Identifying the genetic variants that increase the risk of type 2 diabetes (T2D) in humans has been a formidable challenge. Adopting a genome-wide association strategy, we genotyped 1161 Finnish T2D cases and 1174 Finnish normal glucose-tolerant (NGT) controls with >315,000 single-nucleotide polymorphisms (SNPs) and imputed genotypes for an additional >2 million autosomal SNPs. We carried out a...

2015
Linn Gillberg Charlotte Ling

Type 2 diabetes mellitus (T2D) is a slowly progressive disease that can be postponed or even avoided through lifestyle changes. Recent data demonstrate highly significant correlations between DNA methylation and the most important risk factors of T2D, including age and body mass index, in blood and human tissues relevant to insulin resistance and T2D. Also, T2D patients and individuals with inc...

2015
Siyi Zhang Bo Wang Jingsong Shi Jing Li

The increased prevalence of obesity and type 2 diabetes (T2D) has become an important factor affecting the health of the human. Obesity is commonly considered as a major risk factor for the development of T2D. However, the molecular mechanisms of the disease relations are not well discovered yet. In this study, the combination of multiple differential expression profiles and a comprehensive bio...

Journal: :American journal of physiology. Regulatory, integrative and comparative physiology 2016
Andres E Carrillo Andreas D Flouris Christophe L Herry Martin P Poirier Pierre Boulay Sheila Dervis Brian J Friesen Janine Malcolm Ronald J Sigal Andrew J E Seely Glen P Kenny

We examined whether older individuals with and without Type 2 diabetes (T2D) experience differences in heart rate variability (HRV) during a 3-h exposure to high heat stress compared with young adults. Young (Young; n = 22; 23 ± 3 yr) and older individuals with (T2D; n = 11; 59 ± 9 yr) and without (Older; n = 25; 63 ± 5 yr) T2D were exposed to heat stress (44°C, 30% relative humidity) for 3 h. ...

2017
Jiaxin Tan Yu You Fei Guo Jianhua Xu Haisu Dai Ping Bie

Pancreatic cancer has a five-year overall survival rate <5%, a situation that has not improved since for 40 years. Diabetes mellitus including type 2 diabetes mellitus (T2D) is a suspected risk factor for the development of pancreatic cancer and nearly 45% of the pancreatic cancer cases are likely to present as new onset diabetes cases; however, the nature of association between T2D and pancrea...

2017
Ya-Hui Ding Tie-Ming Wei Lin-Yan Qian Yuan Ma Di-Bo Lao Bin Yao Jie Pang

In this study, we investigated the distribution of vitamin D and its association with carotid atherosclerotic plaque (CP) in Chinese type 2 diabetic (T2D) patients. We performed a cross-sectional study in 210 T2D and 94 age- and gender-matched nondiabetic patients during winter months, by determining serum 25-hydroxyvitamin D (25(OH)D) levels in both diabetic and nondiabetic controls. We carrie...

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