OBJECTIVE The aim of this study is to assess if N-Acetylcysteine (NAC) changes the Ischemic Preconditioning (IP) in isolated rat hearts using only one cycle of IP. METHODS Heart Rate (HR), Coronary Flow (CF) and Myocardial Contractility (dP/dt) were registered in 30 Wistar rat's hearts. After anesthesia the hearts were removed and perfused with Krebes-Hensleit equilibrated solution with 95% o...

BACKGROUND The purpose of this study is to evaluate the disease-free survival (DFS) and overall survival (OS) of patients with stage IIB osteosarcoma at a single institution for 20 years and to compare the results according to the chemotherapy protocols. METHODS From Jan 1988 to Nov 2008, 167 patients with osteosarcoma were treated at our hospital and among them, 117 patients (67 males and 50...

Dairy fat contains high amounts of saturated fatty acids (FA), which are associated with cardiovascular disease (CVD) risk. Manipulation of dairy cows nutrition allows to decrease the saturated FA content of milk fat, and is associated with increases either in conjugated linoleic acid (CLA) and trans-11-C18:1 contents, or in trans-10-C18:1 content. CLA putatively exhibits beneficial properties ...

This report describes a special case of thoracic spinal canal stenosis, which is rarely mentioned in the literature. Thoracic spinal canal stenosis is unusual because it is caused by comprehensive elements and involves multiple segments of the thoracic spine. Compared with the cervical spinal stenosis and lumbar spinal stenosis, thoracic spinal canal stenosis has lower morbidity. This patient u...

We performed macroscopic and single-channel current measurements on wild-type (WT) and two mutant muscle-type nicotinic acetylcholine (ACh) receptor channels transiently expressed in HEK-293 cells. The mutants contained polar-to-nonpolar substitutions at the 10' (alpha(2)S10'A beta T10'A gamma delta) and 6' positions (alpha(2)S6'A beta gamma delta S6'A) in the M2 pore region of the channel. We ...

Essential oils (EOs) from plant extracts have been reported to have an antibacterial activity against gram-negative and gram-positive bacteria. Several of the gram-positive bacteria are involved in ruminal biohydrogenation of fatty acids (FAs), thus suggesting that feeding EOs could lower biohydrogenation of FA because of a decrease in the number of bacteria involved in that process. As a resul...

This document contains the responses to the T10 Letter Ballot comments on forwarding SAM-2 to first public review. The summary of the T10 Letter Ballot results can be found in 02-123r1. All references to SAM-2 PDF pages are based on sam2r23.pdf. r0 All comments from 02-123r1 included. Some comments noted for discussion during the May T10 meeting week. Many comments unprocessed. r1 Resolutions o...

SEZARYEN AMELİYATLARINDAKİ SPİNAL ANESTEZİ UYGULAMALARINDA, ENJEKSİYON HIZININ, HİPOTANSİYON VE EFEDRİN DOZLARI ÜZERİNE ETKİLERİ
 ÖZET
 AMAÇ
 Gebelerde spinal anestezinin hipotansiyon etkisinden kaçınmak için çeşitli yöntemler kullanılmaktadır. Biz de çalışmamızda, sezaryen operasyonlarındaki hız faktörünün hemodinamiye etkisini değerlendirmek amacıyla, anestezi girişimlerinde, 3...

Background : The historical evidence of the use of “general spinal anesthesia” introduced by Thomas Jonnesco in 1909 for the surgeries of the skull, head, neck and thorax puncturing the subarachnoid space (SAS) between 1 and 2 thoracic vertebra producing perfect and deep analgesia for the above mentioned area influenced to puncture SAS at 10 thoracic vertebra (T10) in place of puncturing SAS be...

Lipid droplets (LD) in porcine oocytes form a dark mass reaching almost all cytoplasm. Herein we investigated changes in fat areas, cytoplasmic tone and LD morphology during in vitro maturation (IVM) of porcine oocytes cultured with 100 μM trans-10, cis-12 conjugated linoleic acid (t10,c12 CLA) or 10 μM forskolin at different time periods. Four groups were constituted: control, excipient, t10,c...