Systemic SarcoidosisWith Unique Vulvar Involvement Sarcoidosis is a complex, multisystem disease with an unclear cause.1 Research suggests that the pathogeneticmechanism of sarcoidosis is dysregulation of the immune system in individuals with a genetic predisposition who are subsequently exposed to inciting environmental agents.2 Cutaneous sarcoidosis is often one of the earliest clinical signs...

Sarcoidosis is a systemic disease of unknown etiology. Skin lesions occur in about a quarter of patients with sarcoidosis and specific manifestations include erythema nodosum, maculopapular eruption, plaques, lupus pernio and scar sarcoidosis. A 39-year old male presented with cutaneous involvement of sarcoidosis. The skin biopsy revealed non-caseating granuloma. Our patient had skin manifestat...

Toxic epidermal necrolysis (TEN) is a rare disease in absolute numbers with an incidence of 2 cases per million people per year. Most cases of TEN are caused by drugs, but certain infectious diseases may have an impact on the risk. There are rare reports of TEN occurring without history of drug ingestion in systemic lupus erythematosus (SLE), appearing similar to cutaneous lupus and early TEN m...

orf is a mucocutaneous disease that occurs when non-intact skin comes into contact with contaminated sheep saliva. the lesions may complicate to lymphangitis or secondary bacterial infection, but systemic complications such as erythema multiforme, maculopapular rash, and generalized lymphadenopathy are rare. in this paper, we present two cases of erythema multiforme following orf disease.

Nocardiosis is a rare infection that in more frequent in patients with systemic lupus Erythematosus and its clinical manifestations are nonspecific.while concurrent treatment by corticosteroids is an independent risk factor for nocardiosis it increases both diagnostic and mangement problems.this article presents a 35 years old woman who has systemic lupus Erythematosus.she was hospitalized due ...

background: systemic lupus erythematosus is a kind of multi-system autoimmune disorder with unknown aetiology and it produces antibodies against various tissues. case presentation:the patient wasa 44-year-old woman with a history of systemic lupus erythematosus for approximately five years, along with underlying diseases including peptic ulcers, asthma, hypertension and diabetes in the past 10 ...

background: systemic lupus erythematous is an autoimmune disease associated with atherosclerotic manifestations or metabolic disturbance due to inflammation. the aim of this study was to determine frequency of metabolic syndrome (mets) in sle compared to healthy controls. methods: in this cross-sectional study, 150 sle patients and 220 healthy volunteers were enrolled. mets was diagnosed accord...

Background: Systemic Lupus Erythematosus is a kind of multi-system autoimmune disorder with unknown aetiology and it produces antibodies against various tissues. Case Presentation:The patient wasa 44-year-old woman with a history of Systemic Lupus Erythematosus for approximately five years, along with underlying diseases including peptic ulcers, asthma, h...

"Lupus", from the Latin in the 19th century, had appeared in the West before and after the medical literature. In 1828, the French dermatologist Bette (Biett) firstly reported such a patient: facial skin has erythema the same as the the wolf bites. To the mid-19th century, there was a doctor named Carson Musharraf formally using the "lupus" (lupus erythematosus, LE) as the medical terminology, ...

RATIONAL Nodular cutaneous lupus mucinosis is regarded as a distinctive cutaneous mucinosis deposition with systemic lupus erythematosus(SLE). All typical cases occurred as asymptomatic cutaneous papules, nodules, or plaques on the trunk, upper and lower extremities, and face. Histopathology is mainly revealed abundant mucin deposits among splayed collagen bundles in the dermis. At the same tim...