AIMS/BACKGROUND This study was undertaken to confirm the association between diffuse retinal pigment epitheliopathy (DRPE) and systemic corticosteroid therapy. This finding can be of help in determining an aetiological factor in DRPE and associated diseases. Corticosteroids may contribute to the development of leakage in the presence of a retinal pigment epitheliopathy or central serous chorior...

UNLABELLED The increasing number of patients affected by chronic obstructive pulmonary disease (COPD) and associated exacerbations has led to both rising hospital admissions and significant economic impact. Evidence-based guidelines have been formulated for COPD management recommending the use of low dose, oral corticosteroid therapy in the treatment of exacerbations. However, fewer than 50% of...

Septic shock is characterized by uncontrolled systemic inflammation that contributes to the progression of organ failures and eventually death. There is now ample evidence that the inability of the host to mount an appropriate hypothalamic-pituitary and adrenal axis response plays a major in overwhelming systemic inflammation during infections. Proinflammatory mediators released in the inflamed...

www.pharmacypractice.org (ISSN: 1886-3655) 162 ABSTRACT The increasing number of patients affected by chronic obstructive pulmonary disease (COPD) and associated exacerbations has led to both rising hospital admissions and significant economic impact. Evidence-based guidelines have been formulated for COPD management recommending the use of low dose, oral corticosteroid therapy in the treatment...

The decision to treat a patient with sarcoidosis is dependent on many factors, the most important being whether the patient is symptomatic. Initial systemic therapy for symptomatic sarcoidosis usually includes corticosteroids. However, most symptomatic patients will require months to years of therapy. Therefore, alternatives to corticosteroids have been studied. This review will give a brief ov...

Although allergic contact dermatitis (ACD) due to corticosteroids is a well-known and relatively common phenomenon, the systemic administration of corticosteroids only rarely produces skin reactions (systemic contact dermatitis [SCD]). We present the case of a patient with ACD to various corticosteroids, and who subsequently developed SCD to multiple systemic corticosteroids. A 47-year-old man ...

We report the case of a female child with Down's syndrome affected by idiopathic pulmonary haemosiderosis (IPH), who was successfully treated with hydroxychloroquine. First-line conventional treatment of IPH is traditionally based on systemic corticosteroids; however, many steroid-sparing agents are being increasingly used as adjuncts to corticosteroids in children with recurrent or refractory ...

purpose : to report a patient with orbital pseudotumor masquerading as orbital cellulitis case report : a 42-year-old woman was referred to orbit and oculoplastic clinic with 6 days history of left orbital pain, proptosis, lid edema and fever. clinical finding included severe lid edema, chemosis, conjunctival injection and severe restriction in extraocular motility. she was diagnosed as orbital...

A 4-year-old girl with seronegative systemic juvenile rheumatoid arthritis developed acute cardiac tamponade. Pericardiocentesis and systemic corticosteroids resulted in complete recovery of the pericardial involvement. This was followed by complete remission of rheumatoid disease.