OBJECTIVE To determine the reliability of serological tests in detecting syphilis in a factory worker cohort and examine the impact of concurrent HIV infection on serological tests for syphilis. METHOD Reactions to non-treponemal and treponemal antigens were tested using sera from a cohort of 3401 factory workers in Harare, Zimbabwe. The participants consented to regular testing for syphilis,...

background: unsafe transfusion practices put patients at high risk of transfusion transmissible infections. we aimed to evaluate the prevalence of transfusion transmissible infections (including human immunodeficiency virus [hiv] 1 and 2, hepatitis b virus [hbv], hepatitis c virus (hcv) and syphilis) during a period of 18 months among blood donors in the blood bank of lady hardinge medical coll...

Syphilis in pregnancy can cause considerable fetal and neonatal morbidity and mortality. It is endemic in the developing world but it is now resurgent in the developed world. Maternal syphilis can result in fetal infection leading to fetal and neonatal harm. Mid-trimester miscarriages, stillbirths, low birth weight, prematurity, congenital syphilis and neonatal deaths are all the results of syp...

The incidence of early infectious syphilis in Singapore rose from 8.7 per 100,000 in 1980 to 25 per 100,000 in 1984. In this epidemiological study of 100 patients with early syphilis, 70 were men, the mean age was 31.7 (range 17 to 68) years, 25 patients had primary syphilis, 47 secondary syphilis, and the remaining 28 had early latent syphilis. Female prostitutes were cited as sources of infec...

Syphilis in pregnancy remains an important medical condition due to its consequences. We present two cases of young pregnant women who were diagnosed syphilis during their antenatal visit. The first case was a 29-year-old Malay lady diagnosed with syphilis during the first trimester of pregnancy, while the second case was a 21-year-old Chinese lady diagnosed with syphilis during the third trime...

ABSTRACT Objectives: to investigate factors associated with the occurrence of congenital syphilis in pregnant women and describe cases this disease regarding justification for notification aspects related newborn. Method: cohort study, data collection between July September 2017 which included 158 diagnosed during pregnancy, reported 2013 2015. The characteristics newborns are presented descrip...

BACKGROUND Syphilis infection may potentiate transmission of human immunodeficiency virus (HIV). We sought to determine the extent to which HIV acquisition was associated with syphilis infection within an HIV preexposure prophylaxis (PrEP) trial and whether emtricitabine/tenofovir (FTC/TDF) modified that association. METHODS The Preexposure Prophylaxis Initiative (iPrEx) study randomly assign...

Syphilis Syphilis, a disease caused by the Treponema pallidum bacterium continues to be an important public health problem. Syphilis is a sexually transmitted infection (STI) and can be transmitted by all types of intimate contact including genital, oral, and anal sex. Use of a condom during all sexual activity can reduce the risk of infection. Individuals who are infected with the human immuno...

Syphilis is a systemic infectious disease caused by sexual or congenital transmission of the bacterium Treponema pallidum (T. pallidum). Syphilis causes a variety of symptoms corresponding to stages of infection (primary, secondary, tertiary) and no symptoms during latent stages. Late-stage syphilis includes gummatous, cardiovascular, and neurological complications that can lead to significant ...

Syphilis remains widespread worldwide, with increasing rates among men who have sex with men. This paper reviews available evidence regarding syphilis transmission, including data on: sexual transmission (transmission probability per sexual partnership), vertical transmission, transmission via blood products and organ donation, and other rare modes of transmission. In addition, host susceptibil...