Thymomas are rare neoplasm arising in thymic epithelial cells and are the most common neoplasm in the anterior mediastinum. Although thymomas are often associated with autoimmune diseases, the incidence of extra-thymic neoplasia is higher in patients with thymoma than in the general population.1 Published series have focused on the incidence of both extra-thymic malignancies detected after and ...

Gynecologic malignancies may have similar histological characteristics. This may lead to difficulties in determining the origin of the cancer and to distinguish a synchronous neoplasm from a metastatic cancer in advanced cases. Recently, we treated a 59-year-old patient with adenocarcinoma of the uterine cervix, endometrium, fallopian tubes, and ovaries. It was difficult to determine whether th...

We report our experience of a concurrent robot assisted distal gastrectomy and partial nephrectomy for synchronous early gastric cancer and renal cell carcinoma. A 55-year-old female patient was diagnosed with early gastric cancer on screening endoscopy. Abdominal computed tomography showed an incidental right renal cell carcinoma. Robot assisted distal gastrectomy was performed, followed by pa...

Herein, we report an unusual case of a 78-year-old woman with synchronous presentation of sigmoid cancer and a nonfunctioning primary adrenal cortex carcinoma, who developed superior vena cava syndrome due to metastatic lymphadenopathy from the latter malignancy. Our case suggests that adrenal incidentalomas during initial staging evaluation after cancer diagnosis are not always "innocent" and ...

The synchronous occurrence of GIST and other primary gastrointestinal malignancies has been rarely reported. We report the case of an 84 year-old female who presented with a rectal blood loss. Total coloscopy revealed a stenotic lesion at sigmoid colon covered by endoscopically healthy mucosa and also a massive polypoid cecal mass. The patient underwent left subtotal colectomy and ileorectal J-...

This article reviews adrenal cortical carcinoma (ACC), especially associated synchronous and metachronous malignancies. The authors will discuss the genetic lesions associated with ACC, the clinical presentation, diagnosis, and treatment options. We hope to provide a thorough and updated review of this rare malignancy.

Hidden renal mass is not evident during severe inflammation such as acute pyelonephritis, pyonephrosis, or renal abscess. Deceptive inflammatory presentations that can occur in aggressive synchronous renal malignancies can significantly delay the diagnosis of cancer. Herein, we report a case of acute pyelonephritis involving overlooked renal cell carcinoma.

CONTEXT Synchronous malignancies affecting both the major and minor papilla are rare and are usually of endocrine origin. CASE REPORT A 60-year-old female presented with a two-week history of progressive jaundice and pruritus. Evaluation revealed features of a periampullary malignancy. A Whipple pancreaticoduodenectomy was done. There was a growth in the ampulla of Vater and another in the re...

Diagnosis of synchronous primary genitourinary tumors are uncommon. Thus far, about 50 cases of synchronous renal tumors have been reported in the literature. We present for the first time a case of a 83-year-old man presenting in the same kidney two separate primary malignancies, a TCC of the renal pelvis and a papillary renal cell carcinoma Type 1. Considered the increased incidence of genito...

We read with great interest the article entitle “Chronic lymphocytic lymphoma and concomitant renal cell carcinoma (Clear Cell Type): Review of the literature”, written by Uz et al. [1] and published in a recent issue of your journal. Here, we would like to emphasize some points about this review of the literature. Previously, we also reported 3 cases with hematological malignancies and renal c...