Thirty-two crossbred lambs (BW = 31.2 ± 4.7 kg; 16 females, 16 males) housed in individual pens were used to investigate the relationship between nutrient supply and taste preferences in ruminants. Experiment 1 determined whether an imbalanced CP supply would alter preferences for feeds containing flavors designed to elicit either umami (U) or a mixture (1/3:1/3:1/3) of umami, sweet, and bitter...

Aspartame is the methylester of N-alpha-aspartyl-Lphenylalanine, a polypeptide widely employed as an artificial, intense synthetic sweetener, having none or insignificant caloric values and a sweeting power higher than that of sucrose. Its use in pharmaceutical products and in nearly 6000 food products, has been approved; among its consumers are those that replace natural foods by "light" ones ...

Introduction: Dental caries is a disease that produced by the dissolution of local chemical surfaces teeth caused product microbial fermentation from dietary carbohydrates in biofilm attached to teeth. Sugar especially sucrose most important factors etiology dental caries. Dietary modification have been recommended order reduce fermentable carbohydrate intake needed cariogenic microorganism pro...

Aspartame, a widespread sweetener used in many food products, is considered as a highly hazardous compound. Aspartame was discovered in 1965 and raises a lot of controversy up to date. Astrocytes are glial cells, the presence and functions of which are closely connected with the central nervous system (CNS). The aim of this article is to demonstrate the direct and indirect role of astrocytes pa...

To explore reward substitution in the context of voluntary exercise, female mice from four replicate high-runner (HR) lines (bred for wheel running) and four non-selected control (C) lines were given simultaneous access to wheels and palatable solutions as competing rewards (two doses of saccharin [0.1, 0.2% w/v]; two doses of common artificial sweetener blends containing saccharin [Sweet 'N Lo...