in recent years, biosurfactants due to wide applications in chemical, petroleum, food andpharmaceutical industries, have been widely considered by researchers. biosurfactants are produced by aseries of microorganisms, so it is important to screen culture medium and operating conditions in miniaturized bioreactors prior to scaling up to large bioreactors.in this study, using a kind of miniaturiz...

Bacillus subtilis strain BIA was used for the production of bioactive lipopeptides. Different extraction and purification methods were assayed as liquid-liquid extraction, and acid and ammonium sulfate precipitation followed by TLC, SPE, and gel filtration. Active fractions were further purified using RP-HPLC. The molecular mass of the purified product from HPLC was determined through Tris-Tric...

Growing tendrils of aflagellate hag mutants of Bacillus subtilis were found to show an avoidance response when colonizing a semi-solid medium, suggesting a tip-to-tip communication mechanism between colonies. There may be a second sensing mechanism involved in shaping the morphology of tendrils. Tendril growth in B. subtilis was dependent on and possibly shaped by the release of surfactin, a bi...

in recent years, biosurfactants due to wide applications in chemical, petroleum, food andpharmaceutical industries, have been widely considered by researchers. biosurfactants are produced by aseries of microorganisms, so it is important to screen culture medium and operating conditions in miniaturized bioreactors prior to scaling up to large bioreactors.in this study, using a kind of miniaturiz...

As one of the most effective biosurfactants reported to date, lipopeptides exhibit attractive surface and biological activities have great potential serve as biocatalysts. Low yield, high cost production, purification hinder large-scale applications lipopeptides. Utilization waste materials low-cost substrates for growth biosurfactant producers has emerged a feasible solution economical product...

Fungi of the genus Fusarium are economically significant pathogens in most wheat-growing regions worldwide. The biocontrol agents Bacillus velezensis BZR 336 g and 517 were tested for growth inhibition F. graminearum 4. results demonstrated that strains capable deforming destroying hyphae. modified bioautography technique showed produce iturin A surfactin, which probably explains mechanism path...

Surfactin, one of the most powerful biosurfactants, can be widely applied in agriculture, food, and pharmaceutics. The purpose present study was to establish suitable indicators for a rapid detection method that confirm surfactin productivity cheonggukjang. In study, changes total number bacteria were quantified according fermentation time chenggukjang. Furthermore, physicochemical factors, suc...

Lipopeptide biosurfactants produced by Bacillus sp. were assessed regarding their antimicrobial activity against foodborne pathogenic and food spoilage microorganisms. Both Gram-positive Gram-negative bacteria found not to be susceptible these lipopeptides. However, mycosubtilin mycosubtilin/surfactin mixtures very active the filamentous fungi Paecilomyces variotti Byssochlamys fulva , with min...

Despite great efforts have been made worldwide, the coronavirus disease 19 (COVID-19) still has not a definitive cure, although availability of different vaccines are slowing down transmission and severity. It shown that surfactin, cyclic lipopeptide produced by Bacillus subtilis, is molecule able to counteract both SARS-CoV-1, MERS-CoV HCoV-229E coronaviruses. In this study potential antiviral...