conclusions primary extracranial meningiomas (pems) without intracranial origin are very rare and because of their slow growing nature are initially managed by primary care physicians. case presentation we report a case of slowly progressing extracranial meningioma that was presented in a young adult woman. the tumor was asymptomatic but large enough to cause cosmetic discomfort. patient underw...

meningioma is usually a benign central nervous system (cns) tumor. metastasis is rare; however if it does occur the most metastatic sites are the liver and lungs. here, two cases of cns meningioma with metastasis to cervical lymph nodes are reported. the first case, a 48 year-old man developed cervical lymph node metastasis nine years after primary tumor diagnosis. the second case, a 23 year-ol...

OBJECTIVE To investigate the potential involvements of E-cadherin and beta-catenin in meningioma. METHODS Immunohistochemistry staining was performed on samples from patients with meningioma. The results were graded according to the positive ratio and intensity of tissue immunoreactivity. The expression of E-cadherin and beta-catenin in meningioma was analyzed by its relationship with WHO2007...

An infant boy presented at birth with a large mass protruding from the left orbit that significantly displaced the left globe laterally and inferiorly . Biopsy of the mass was performed the next day, yielding the diagnosis of infantile myofibromatosis. Therapy was considered but the parents opted for no treatment, although they agreed to yearly CT follow-up examinations. The CT study at the tim...

Hemangioblastoma in the suprasellar region is rare. We present a case of a suprasellar hemangioblastoma that underwent surgical resection using an extended endoscopic transsphenoidal approach. A 64-year-old female patient presented with headache and decreased visual acuity for the last four years, computed tomography (CT) and magnetic resonance imaging (MRI) revealed a 2.5 cm irregular lesion i...

Suprasellar tumors with compression of the optic chiasm are associated with an impaired sleep-wake rhythm. We hypothesized that this reflects a disorder of the biological clock of the human brain, the suprachiasmatic nucleus (SCN), which is located just above the optic chiasm. In order to test this hypothesis, we investigated the expression of two key neuropeptides of the SCN, that is, arginine...

Meningioma is a common pathology in the central nervous system (CNS). It arises from the arachnoid cap cells of the arachnoid villi in the meninges, which envelop the brain and spinal cord. Therefore, a meningioma can occur anywhere from the vertex to the spine. It is often named according to its anatomical location. For example, a meningioma abutting the sphenoid bone between the frontal and t...