The importance of zinc in normal immune function and of its deficiency in immune dysfunction has led to increased interest in its role in nutrition and immunity in human immunodeficiency virus type 1 (HIV) infection. Zinc deficiency produces reversible immune dysfunction, particularly of Tlymphocyte cell-mediated immunity. In developing countries where zinc deficiency is prevalent, zinc supplem...

INTRODUCTION Zinc supplementation reduces the severity, duration and recurrence of childhood acute diarrhoea. These beneficial effects of zinc in the treatment of diarrhoea led to the inclusion of a 10-14 days treatment regimen by the WHO/UNICEF. This study assessed the level of knowledge and use of zinc supplementation in the management of childhood diarrhoea among health care workers in publi...

Occurrence of zinc deficiency in adult sickle cell anemia subjects has been reported previously. Improvement in secondary sexual characteristics, normalization of plasma ammonia and serum testosterone levels, and reversal of dark adaptation abnormality and anergy following zinc supplementation to sickle cell anemia subjects have been observed. In this paper we report the results of a controlled...

Background: Micronutrients deficiency is one of the most health problems in the world. Iron and zinc deficiency and their interaction with vitamin A are important, too. The aim of this study was to investigate the effects of supplementation of iron and zinc, alone or combined, on vitamin A status of primary school children. Material and methods: The study was a randomized double-blind clinica...

The clinical manifestations of zinc deficiency and anorexia nervosa are remarkably similar, and a number of studies have demonstrated that there may be a positive correlation between zinc therapy and the rate of recovery of anorexia nervosa patients. However, because of the different interpretations of the results of these studies, the use of zinc supplementation varies. This article examines t...

BACKGROUND Maternal zinc deficiency during pregnancy may be widespread among women in developing countries, but few data are available on whether prenatal zinc supplementation improves maternal and neonatal zinc status. OBJECTIVE We studied whether maternal zinc supplementation improved the zinc status of mothers and neonates participating in a supplementation trial in a shantytown in Lima, P...

OBJECTIVE In a zinc supplementation trial (with a significant impact on diarrheal morbidity), to evaluate effect of zinc supplementation on cellular immune status before and after 120 days of supplementation. DESIGN A double blind, randomized controlled trial with immune assessment at baseline and after 120 days on supplement. SETTING Community based study in an urban slum population. SUB...

Title: Effect of vitamin-D, zinc and copper supplementation in HIV-positive pregnant women and co-relation with CD4 countsa randomized double blinded placebo controlled study. Background: The main aim of this study was to evaluate the effect of vitamin D, zinc and copper supplementation in HIV-positive pregnant women and its c0-relation with CD4 counts. Methods: A total of 195 HIV-positive preg...

BACKGROUND Even though the WHO currently recommends zinc for diarrhea management, no consensus has been reached with respect to routine distribution of zinc for preventive reasons. We reviewed the health impact of preventive zinc interventions, and evaluated the relative cost effectiveness of currently feasible interventions. METHODS Using the latest relative risk estimates reported in the li...

We aimed to examine the effects of zinc supplementation on nutritional status, lipid profile, and antioxidant and anti-inflammatory therapies in maintenance hemodialysis (MHD) patients. We performed a systematic review and meta-analysis of randomized, controlled clinical trials of zinc supplementation. Metaregression analyses were utilized to determine the cause of discrepancy. Begg and Egger t...