Theranostic nanoparticles based on superparamagnetic iron oxide (SPIO) have a great promise for tumor diagnosis and gene therapy. However, the availability of theranostic nanoparticles with efficient gene transfection and minimal toxicity remains a big challenge. In this study, we construct an intelligent SPIO-based nanoparticle comprising a SPIO inner core and a disulfide-containing polyethyle...

in the current paper,nanostructured nickel oxide (nio) were synthesized by co-precipitation method using nickel(ii) chloride hexahydrate (nicl2.6h2o) and sodium hydroxide (naoh) as starting material. structural, optical and magnetic properties of nanostructures were characterized by x-ray diffraction (xrd), scanning electron microscopy (sem), atomic force microscope (afm), uv–vis absorption; fo...

Early diagnosis of cartilage disease at a time when changes are limited to depletion of extracellular matrix components represents an important diagnostic target to reduce patient morbidity. This report is to present proof of concept for nanoparticle dependent cartilage barrier imaging in a large animal model including the use of clinical magnetic resonance imaging (MRI). Conditioned (following...

Superparamagnetic iron oxide nanoparticles are candidate contrast agents for magnetic resonance imaging and targeted drug delivery. Biodistribution and toxicity assessment are critical for the development of nanoparticle-based drugs, because of nanoparticle-enhanced biological reactivity. Here, we investigated the uptake, in vivo biodistribution, and in vitro and in vivo potential toxicity of m...


 Nickel ferrite (NiFe2O4) is one of the spinel nanoparticles that useful for scientific and technological, like biomedicine. This paper discusses synthesis NiFe2O4 by various methods. aims to find out most efficient method which are used as hyperthermia agents in The a literature study an article with publications from 1956-2018 discussing several methods syntheses, such sol-gel, hydrothe...