In the presence of phentolamine, stimulation of the cat splanchnic nerve decreased the resistance of the superior mesenteric arterial bed. This effect was not significantly influenced by sulpiride. Sulpiride, in the presence of phentolamine, did not inhibit the decrease in resistance in animals pretreated with guanethidine but propranolol or ablation of the adrenal glands prevented the effect o...

brain's waves are produced by spontaneous activity of neurons. these waves are changed by neurotransmitters in the central nervous system (cns). concentration of these neurotransmitters can be changed by various drugs and total power of brain waves also increase or decrease by these drugs. in this research effect of quinpirol and sulpiride on the brain waves was investigated. male wistar r...

Roxindole, a DA D2 receptor agonist (2-16 mg/kg) produced dose-dependent increase in percentage antinociception. The effect which was blocked by DA D2 antagonist (-)sulpiride (50 mg/kg) and 5-HT1A receptor antagonist (-) pindolol (5 mg/kg). Roxindole (4 and 8 mg/kg) reversed both naloxone (20 mg/kg)-induced hyperalgesia and reserpine (2 mg/kg)-induced hyperalgesia. This reversal was sensitive t...

In the presence of phentolamine, stimulation of the cat splanchnic nerve decreased the resistance of the superior mesenteric arterial bed. This effect was not significantly influenced by sulpiride. Sulpiride, in the presence of phentolamine, did not inhibit the decrease in resistance in animals pretreated with guanethidine but propranolol or ablation of the adrenal glands prevented the effect o...

Background: Usage of some atipycal antipsychotic drugs like sulpiride has severed effects on male fertility by impressions on sexual hormones secretion. These hormones regulate male germ cells proliferation and differentiation. In the present study we sought to elucidate the impact of sulpiride on serum prolactin and FSH concentration. Also effect of FSH on spermatogonium A/B (repopulation inde...

Background: Prescription of the atypical antipsychotic drugs like as Sulpiride for the treatment of schizophrenic patients was increased because of their less side effects. This study was aimed to evaluate the effect of sulpiride on hormonal milieu of adult male mice namely their serum level of prolactin and sexual hormones. Materials and Methods: 24 adult male mice were divided in three groups...

introduction: the protective and antisecretory effects of dopamine agonists on the stomach have been already reported, but the effect of bromocriptine (d2 dopamine agonist) on histamine stimulated gastric acid secretion (gas) needs to be investigated. methods: for gastric sampling, animals were anesthetized and a polyethylen tube was introduced into the stomach through esophagus. a cannula was ...