BACKGROUND The acute inflammatory response following mesh implantation has been often evaluated in vitro and in animal models. The aim of this study was to evaluate the acute inflammatory response near the prosthesis in human by analysing some inflammatory indicators. METHODS We used a cohort of twelve male patients affected by midline incisional hernia, who were admitted for surgical mesh re...

We prospectively randomised 78 patients into two groups, 'drains' or 'no drains' to assess the effectiveness of suction drains in reducing haematoma and effusion in the joint and its effect on wound healing after total knee replacement. Ultrasound was used to measure the formation of haematoma and effusion on the fourth post-operative day. This was a semi-quantitative assessment of volume estim...

In this experimental trial , 133 patients with single long bone fracture requiring surgery, admitted in Shahid Mohammadi Hospital (Bandar Abbas/Iran) from June 2002 to April 2003, were randomly devided into two groups. In the first group (72 individuals), after the completion of the operation a single hemovac drain was inserted, while in the second group (61 patients) no drain was used. The two...

To obtain early healing of the perineal wound after excision of the rectum has always been one of the problems of the operation. Few surgeons now use oiled silk and packing, with frequent irrigations, until the wound is healed. Healing of the perineal wound was very slow when this method was used. Complete primary closure without drainage is not a satisfactory method of treatment. Most surgeons...

BACKGROUND The use of negative pressure in the dressing of split skin grafts has been shown to promote healing by a variety of mechanisms, including a decrease in interstitial oedema, an increase in perfusion and a decrease in bacterial colonisation. Vacuum-assisted closure (VAC) dressings have, until now, been used as the archetype for negative pressure dressings and have been reflected as suc...