introduction: a cleft lip with or without a cleft palate is one of the major congenital anomalies observed in newborns. this study explored the risk factors for oral clefts in gorgan, northern iran.  materials and methods: this hospital-based case-control study was performed in three hospitals in gorgan, northern iran between april 2006 and december 2009. the case group contained 33 newborns wi...

AIM To examine the prevalence of different types of dental anomalies in children with nonsyndromic cleft lip, unilateral cleft lip-palate, and bilateral cleft lip-palate. MATERIALS AND METHODS A sample of 90 patients (aged 4-20 years) affected by isolated cleft lip, unilateral and bilateral cleft lip and palate was examined. Cleft patients were classified into one of three groups according to...

background cleft lip and palate as the most common congenital defect of oral cavity possesses a heavy socioeconomic burden for both the child and parents. nasoalveolar molding (nam) has received more attention to enhance future facial appearance and function during recent decades case presentation a 21-day old female neonate was referred with a bilateral cleft lip and palate. parents complained...

Subcorneal pustular dermatosis (SCPD, Sneddon-Wilkinson disease) is a rare chronic-relapsing skin disorder that typically manifests as flaccid sterile pustules without systemic symptoms. Although the accumulation of neutrophils is acknowledged to be a hallmark of SCPD, its exact pathomechanism is still not known. Several chemotactic factors have been implicated in neutrophil recruitment and inv...

Cleft lip defects are usually regarded as a single entity, with the assumption that an accompanying cleft palate represents the more severe form. The authors linked data from the Medical Birth Registry of Norway with medical records from two centralized centers to provide a population-based data set. They assessed the distribution of cleft lip only and cleft lip with cleft palate by covariate. ...

background: current methods of closure of the cleft palate result in the formation of scars and impairment of growth. distraction osteogenesis (do) might be an effective means to repair or at least reduce the size of wide clefts. this study investigates the biomechanical aspects of this process. materials and methods: do simulation was applied to reduce the size of a unilateral hard palate clef...

The isolation-with-migration (IM) model is a common tool to make inferences about the presence of gene flow during speciation, using polymorphism data. However, Becquet and Przeworski (2009) report that the parameter estimates obtained by fitting the IM model are very sensitive to the model’s assumptions – including the assumption of constant gene flow until the present. This paper is concerned...

Background and Importance: Symptomatic Rathke’s cleft cyst is a rare lesion that often presents without any symptoms.  Case Presentation: We report a 40-year-old female with symptomatic Rathke’s cleft cyst located in the sellar and suprasellar region. She presented with visual disturbance, headache, weight gain, hypothyroidism and amenorrhea. The patient underwent surgery and ...

The incidence and types of dental trait anomalies found in individuals with cleft lip or cleft palate or both (cleft group), in siblings of the cleft group, and in a group of individuals without cleft lip or cleft palate (noncleft group) were compared. The cleft group had 1.02 anomalies per individual, the sibling group, 0.38; and the noncleft group, 0.17. The frequency of occurrence of thick-c...