1. Conjunctival tissue derived from alien and native American white persons in New York City, having trachoma in an advanced stage, has been used successfully to induce in Macacus rhesus monkeys characteristic granular conjunctivitis. The transfer of infection was effected either by a single subconjunctival injection, or by repeated swabbing with conjunctival secretions. 2. Pathogenic strains o...

Subconjunctival emphysema is a condition that must theoretically exist in severe subcutaneous emphysema due to the laxity of the conjunctival tissues. However, this is generally obscured by associated periorbital emphysema and is hidden from view. We present documented evidence of subconjunctival emphysema in the absence of periorbital emphysema. A 53 year old man was admitted with a large righ...

purpose: to report an unusual ocular presentation of a relapse of acute lymphoblastic leukemia. case report: a 9-year-old girl presented with a subconjunctival mass and ipsilateral preauricular lymphadenopathy. she had history of acute lymphoblastic leukemia (all) in remission but had a normal blood cell profile. because of corneal dellen formation and enlargement of the mass over a 2-week peri...

Purpose. To measure the chemotherapeutic effects of focal melphalan (intravitreal and subconjunctival) on tumor burden, hypoxia, and vasculature in LHBETATAG murine retinoblastoma model. Methods. LHBETATAG transgenic mice were treated with a single 1 mcg intravitreal injection of melphalan, 100 mcg subconjunctival injection, or semiweekly 10 mcg subconjunctival injections for 3 weeks. At 1 or 3...

PURPOSE To investigate the immediate effect of intravitreal injection of bevacizumab on intraocular pressure (IOP). METHODS This was a prospective and nonrandomized study. A total of 291 eyes with macular edema or active choroidal neovascularization were submitted to a single 1.25 mg (0.05 mL) bevacizumab intravitreal injection. Intraocular pressure was measured with an Icare(®) tonometer imm...

PURPOSE To evaluate the tear film characteristics of spontaneous subconjunctival hemorrhage patients by Schirmer test I and tear interferometry. METHODS Forty-six spontaneous subconjunctival hemorrhage patients and 46 controls were enrolled in the study. Schirmer test I and tear interferometry were performed in all 92 subjects. The results obtained were compared between the two groups. RESU...

PURPOSE To evaluate the short-term effects of a single subconjunctival injection of triamcinolone acetonide as an adjunct to subconjunctival bevacizumab for prevention of corneal neovascularization in rats. METHODS Chemical cauterization was performed in the central cornea of the right eye in 48 male Sprague-Dawley rats (4 eyes were excluded due to perforation and/or infection). Immediately a...

Dirofilariasis is a worldwide zoonotic filariasis with over 782 cases reported so far from different parts of the world. Human dirofilariasis, caused by Dirofilaria repens, have been reported to occur widely throughout Asia, Europe, and Africa. It has not been widely recognized in India, however; several cases have been reported in last few years. There is probably a focus of human infection wi...

Imidazole, given intraperitoneally to rabbits, inhibited the prostaglandin E1-induced (PGE1) elevation of intraocular pressure. The maximum imidaz-le effect occurred at three to six hours after intraperitoneal infection. The prostaglandin E1-induced aqueous humor protein elevation was reduced markedly in the imidazole-pretreated rabbits. Intravenous administration of imidazole also was effectiv...