نتایج جستجو برای: structureactivity relationship

تعداد نتایج: 553387  

2006
Akhilesh Bajaj

Much of the work on automatic user interface (UI) generation has met with limited success because of the added load on the human designer to use specialized scripts for UI specification. In this research in progress, we propose a methodology applicable to database driven systems that a) automatically infers a draft interface directly from an extended entity relationship (EER) model schema and b...

Journal: :Data Knowl. Eng. 1993
Marco A. Casanova Luiz Tucherman Alberto H. F. Laender

A method for obtaining optimized relational representations of database conceptual schemas in an extended entity-relationship model is first proposed. The method incorporates and generalizes a familiar heuristics to obtain good relational representations and also produces, for each relational structure, an explanation indicating which concepts it represents. Then, a redesign method that, given ...

2014
Meisam Karami

The structure of the current study is based on to the prior studies on supply chain management practices and perceived organizational performance. The objective of the current study is to create a conceptual framework to investigating the link between supply chain management practices and healthcare’s perceived organizational performance that indicates the mediating impact of alliance integrate...

2006
Dooil Kim

Multiple linear regression analysis was performed on the quantitative structureactivity relationships (QSAR) of the triazoloquinazoline adenosine antagonists for human A3 receptors. The data set used for the QSAR analysis encompassed the activities of 33 triazoloquinazoline derivatives and 72 physicochemical descriptors. A template molecule was derived using the known molecular structure for on...

Journal: :Cancer research 1958
D A CLARKE G B ELION G H HITCHINGS C C STOCK

The systematic investigation of purities as antagonists of nucleic acid synthesis in bacteria, viruses, and neoplasms has been under way in these laboratories for a number of years (6, 29, 30, 33, 47, 49). The purines and their analogs have been studied in a wide variety of biological sys tems in an attempt to correlate details of chemical structure with activity. Studies with Lactobacillus cas...

Journal: :علوم مدیریت ایران 0

unreliability of financial statements in iran has urged this country’s financial services industry management to manipulate practices by which they could gain reliable risk scores for borrowers. this research extracts the most influential qualitative factors that would impact the default of a business relationship borrower. solicitation of the factors is done through delphi methodology. the mea...

1999
Yin-tak Woo David Y. Lai Joseph C. Arcos

Since the passage of the Toxic Substances Control Act (TSCA), which requires the U.S.Environmental Protection Agency (EPA) to assess potential toxic effects of new and existing chemicals, structureactivity relationships (SAR) analysis has been extensively and effectively used in the identification of potential health hazards of new (Premanufacturing Notification) industrial chemicals (Arcos, 19...

2006
Thomas Hartung

ECVAM is an international reference centre for the development and validation of alternative testing methods aimed at the replacement, reduction or refinement of the use of laboratory animals in the biomedical sciences, with emphasis on toxicological assessments. ECVAM was established by a communication of the European Commission (SEC 91/1794) to the European Parliament and Council referring to...

2012
John-Bruce D. Green Timothy Fulghum Mark A. Nordhaus

Traditionally antimicrobial devices and applications have leveraged the elution of biocides from devices which were infused with these active molecules. The elution of these agents can, in some cases, limit the application of the device and can potentially lead to unwanted side effects. Following the ground breaking works of Isqueth, Abbott and Walters, surface immobilized antimicrobial agents ...

2013
Yumei Hu Xingyi Zhou

The harmonic index is one of the most important indices in chemical and mathematical fields. It’s a variant of the Randić index which is the most successful molecular descriptor in structure-property and structureactivity relationships studies. The harmonic index gives somewhat better correlations with physical and chemical properties comparing with the well known Randić index. The harmonic ind...

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