Previous studies demonstrated that CSE induces oxidative stress and its consequences on isolated mitochondria obtained from lung, heart and brain which may provide insight into the role of CSE in human health and disease. The present study was carried out to further characterize and compare toxic effect of CSE extract on isolated mitochondria obtained from either a directly contacting tissue (i...

diazinon is an organophosphate which is extensively used in trade and agriculture. due to its widespread application, its toxicity is common. several studies have shown that organophosphates are able to induce oxidative stress by generating free radicals and depletion of endogenous antioxidants. pomegranate seed oil (pso) possesses anti-inflammatory and antioxidant effects. in this study, the e...

In this paper, a new non-contact ultrasonic abrasive finishing mechanism is designed and fabricated. This mechanism combines the function of ultrasonic vibrations and the magnetic abrasive finishing (MAF) process. A permanent magnet which is mounted on a horn has been used as the processing tool. This polishing tool is vibrated at an ultrasonic frequency with piezo-electric actuators. Ultrasoni...

A free-Lagrange numerical method is implemented to simulate the axisymmetric jetting collapse of air bubbles in water. This is performed for both lithotripter shock-induced collapses of initially stable bubbles, and for free-running cases where the bubble initially contains an overpressure. The code is validated using two test problems (shock-induced bubble collapse using a step shock, and shoc...

Crocin, the main constituent of saffron (Crocus sativus L.), is a natural carotenoid which is known for its antioxidant activity. Liver as the organ that metabolizes many chemicals is one of the first position that is at risk of environmental pollutants. It is clear that compounds that exhibit antioxidant properties, scavenging of free radicals and inhibition of lipid peroxidation are expected ...

Cave collapses emerge during the process of oil reservoir development, seriously affecting oil production. To reveal the collapse and failure mechanism of the carbonate cavern with a buried depth of 5600 m in Tahe Oil Field, using a self-developed ultra-high pressure model test system with the intelligent numerical control function, the model simulation material of carbonate rocks developed to ...

6- mercaptopurine (6-mp) is widely used in clinic as an immunosuppressive for treatment of acute lymphocytic leukemia, crohn's disease, and ulcerative colitis with documented unpredictable hepatotoxicity. the potential molecular cytotoxic mechanisms of 6-mp against isolated rat hepatocytes were searched in this study using “accelerated cytotoxicity mechanism screening (acms)” techniques. t...